Evidence map›Paper›PMID 28919714›Full record

ReviewDrug design, development and therapy2017

Radium 223 dichloride for prostate cancer treatment.

Emmanuel Deshayes, Mathieu Roumiguie, Constance Thibault, Philippe Beuzeboc, Florent Cachin, Christophe Hennequin, Damien Huglo, François Rozet, Diana Kassab-Chahmi, Xavier Rebillard and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Drug design, development and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 97 citations in OpenAlex.

  1. Trial
  2. Review
  3. Biokinetic modelling of the exhalation ofRadiation and environmental biophysics · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. EJNMMI radiopharmacy and chemistry · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Laser isotope separation ofScientific reports · 2023
    Article
  15. Review
  16. Review
  17. A Projection-Domain Low-Count Quantitative SPECT Method forIEEE transactions on radiation and plasma medical sciences · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 1 country.

Emmanuel DeshayesRadiobiology Unit, INSERM U1194, Institut du Cancer de Montpellier (ICM).
Mathieu RoumiguieUrology Department, Andrology and Renal Transplantation, CHU Rangueil, Toulouse.
Constance ThibaultMedical Oncology Department, Hôpital Européen Georges Pompidou.
Philippe BeuzebocOncology Department, Institut Curie.
Florent CachinDepartment of Nuclear Medicine, CHU, Clermont-Ferrand.
Christophe HennequinRadiotherapy Department, Hôpital Saint Louis, Paris.
Damien HugloDepartment of Nuclear Medicine, CHRU, Lille.
François RozetUrology Department, Institut Mutualiste Montsouris.
Diana Kassab-ChahmiIntergroupe coopérateur francophone de recherche en onco-urologie, Paris.
Xavier RebillardUrology Department, Clinique BeauSoleil, Montpellier.
Nadine HouédéRadiobiology Unit, INSERM U1194, Institut du Cancer de Montpellier (ICM).
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Universitaire de Lille · FRClinique du Millénaire · FRHôpital Rangueil · FRInstitut Curie · FRInstitute Mutualiste Montsouris · FRIntergroupe Francophone de Cancérologie Thoracique · FRSorbonne Université · FRUniversité Clermont Auvergne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the most common malignant disease in men. Several therapeutic agents have been approved during the last 10 years. Among them, radium-223 dichloride (Xofigo

Indexed as

AnimalsAntineoplastic AgentsBone NeoplasmsDNA Breaks, Double-StrandedHumansMaleProstatic Neoplasms, Castration-ResistantRadioisotopesRadiumTumor MicroenvironmentAntineoplastic AgentsRadioisotopesRadiumradium Ra 223 dichlorideagentsbone metastasisdevelopmentdrugmCRPCmechanism

Identifiers

PMID28919714
PMCPMC5593411
OpenAlexW2752867062

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.