Evidence map›Paper›PMID 28919635›Full record

ReviewNature reviews. Microbiology2017

Aspergillus fumigatus morphology and dynamic host interactions.

Frank L van de Veerdonk, Mark S Gresnigt, Luigina Romani, Mihai G Netea, Jean-Paul Latgé

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 266 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
266citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

266 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
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  10. Biomolecular Corona Remodelling ofJournal of extracellular biology · 2026
    Article
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  13. Microbiology and molecular biology reviews : MMBR · 2026
    Review
  14. Review
  15. Understanding multi-azole resistance inFrontiers in fungal biology · 2026
    Article
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  19. Article
  20. Review

206 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Frank L van de VeerdonkDepartment of Internal Medicine, Radboud University Medical Center.
Mark S GresnigtDepartment of Internal Medicine, Radboud University Medical Center.
Luigina RomaniDepartment of Experimental Medicine, Pathology Section, University of Perugia, Perugia 06132, Italy.
Mihai G NeteaDepartment of Internal Medicine, Radboud University Medical Center.
Jean-Paul LatgéUnité des Aspergillus, Institut Pasteur, 25-28 Rue du Dr Roux, 75015 Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening disease in immunocompromised individuals. The interactions between A. fumigatus and the host environment are dynamic and complex. The host immune system needs to recognize the distinct morphological forms of A. fumigatus to control fungal growth and prevent tissue invasion, whereas the fungus requires nutrients and needs to adapt to the hostile environment by escaping immune recognition and counteracting host responses. Understanding these highly dynamic interactions is necessary to fully understand the pathogenesis of aspergillosis and to facilitate the design of new therapeutics to overcome the morbidity and mortality caused by A. fumigatus. In this Review, we describe how A. fumigatus adapts to environmental change, the mechanisms of host defence, and our current knowledge of the interplay between the host immune response and the fungus.

Indexed as

Host-Pathogen InteractionsAdaptation, PhysiologicalAspergillosisAspergillus fumigatusCell WallDrug Resistance, Multiple, FungalHumansImmunity, Innate

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.