ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2017
Clinical significance of failure to lose weight 10 years after roux-en-y gastric bypass.
Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Long-term Outcome of the Dutch Common Channel Trial (DUCATI): Preservation of Superior Weight Loss Results Without Significant Malnutrition Side Effects.Obesity surgery · 2024Trial
- Trial
- Resting energy expenditure of females mid- to long-term after bariatric surgery: agreement between indirect calorimetry and predictive methods.European journal of clinical nutrition · 2025Article
- Suboptimal Weight Loss 13 Years After Roux-en-Y Gastric Bypass Is Associated with Blunted Appetite Response.Obesity surgery · 2024Article
- Definition, Mechanisms and Predictors of Weight Loss Failure After Bariatric Surgery.Journal of metabolic and bariatric surgery · 2022Review
- Factors associated with quality of life and weight regain 12 years after Roux-en-Y gastric bypass.Surgical endoscopy · 2022Article
- Weight loss before bariatric surgery and its impact on poor versus excellent outcomes at 2 years.Langenbeck's archives of surgery · 2022Article
- First study on the outcomes of biliopancreatic diversion with duodenal switch in Chinese patients with obesity.Frontiers in surgery · 2022Article
- The Positive Impact of Resistance Training on Muscle Mass and Serum Leptin Levels in Patients 2-7 Years Post-Roux-en-Y Gastric Bypass: A Controlled Clinical Trial.Obesity surgery · 2021Article
- Article
- Bariatric surgery reduces long-term rates of cardiac events and need for coronary revascularization: a propensity-matched analysis.Surgical endoscopy · 2020Article
- The Mitigating Effect of Phentermine and Topiramate on Weight Regain After Roux-en-Y Gastric Bypass Surgery.Obesity (Silver Spring, Md.) · 2020Article
- Specific Health Knowledge and Health Literacy of Patients before and after Bariatric Surgery: A Cross-Sectional Study.Obesity facts · 2020Article
- Weight Recidivism After Roux-en-Y Gastric Bypass Surgery: An 11-Year Experience in a Multiethnic Medical Center.Obesity (Silver Spring, Md.) · 2019Article
- Review of multimodal treatment for type 2 diabetes: combining metabolic surgery and pharmacotherapy.Therapeutic advances in endocrinology and metabolism · 2019Review
- Practices Concerning Revisional Bariatric Surgery: a Survey of 460 Surgeons.Obesity surgery · 2018Article
- Efficacy of Utilizing Argon Plasma Coagulation for Weight Regain in Roux-en-Y Gastric Bypass Patients: a Multi-center Study.Obesity surgery · 2018Article
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7 authors.
Funding
Abstract
backgroundAlthough Roux-en-Y gastric bypass (RYGB) induces short-term weight loss and co-morbidity amelioration, long-term data suggest that a subset of patients return to their preoperative body mass index (BMI).
objectivesTo identify the clinical implications of 10-year weight loss failure after RYGB.
settingAn academic teaching hospital.
methodsAdults undergoing RYGB (1985-2004) were included in this study (n = 1087). Absolute weight loss failure was defined as ≤0% reduction in excess BMI 10 years after surgery. Univariate analyses compared co-morbidity rates and resolution by weight loss classification. Multivariable regression modeling analyzed preoperative predictors of 10-year percent reduction in excess BMI and weight loss failure.
resultsComplete follow-up was available for 617 (57%) patients with a 10-year median percent reduction in excess BMI of 57.1%; 10.2% of patients had weight loss failure. Prevalence of all co-morbidities decreased, even in patients with weight loss failure (all P<.05). Compared with patients with successful weight loss, patients with weight loss failure had similar rates of resolution of pre-existing co-morbidities, except for reduced resolution of apnea and cardiac co-morbidities (both P<.05). Risk factors for weight loss failure included lower BMI, nongovernmental insurance, longer travel time to hospital, and year of surgery. Nongovernmental insurance (odds ratio 2.03, P = .036) conferred the highest adjusted odds of weight loss failure.
conclusionsThe vast majority of patients experience dramatic health improvement 10 years after RYGB, even though some patients fail to maintain their weight loss. Renewed focus should be placed on prevention and treatment of chronic disease, with further investigation of weight loss independent mechanisms of health improvement.
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