Evidence map›Paper›PMID 28918889›Full record

ArticleHarmful algae2016

Gene expression patterns in peripheral blood leukocytes in patients with recurrent ciguatera fish poisoning: Preliminary studies.

Maria-Cecilia Lopez, Ricardo F Ungaro, Henry V Baker, Lyle L Moldawer, Alison Robertson, Margaret Abbott, Sparkle M Roberts, Lynn M Grattan, J Glenn Morris

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Harmful algae, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria-Cecilia LopezDepartment of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Ricardo F UngaroDepartment of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Henry V BakerDepartment of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL 32610, USA; Department of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610, USA; Genetics Institute, University of Florida, Gainesville, FL 32610, USA.
Lyle L MoldawerDepartment of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Alison RobertsonMarine Ecotoxicology Lab, Department of Marine Sciences, University of South Alabama & Dauphin Island Sea Lab, USA. Electronic address: arobertson@disl.org.
Margaret AbbottEmerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
Sparkle M RobertsDepartment of Neurology, Division of Neuropsychology, University of Maryland School of Medicine, 110 S., Paca St., 3rd Floor, Baltimore, MD 21201, USA. Electronic address: sroberts@som.umaryland.edu.
Lynn M GrattanDepartment of Neurology, Division of Neuropsychology, University of Maryland School of Medicine, 110 S., Paca St., 3rd Floor, Baltimore, MD 21201, USA. Electronic address: lgrattan@som.umaryland.edu.
J Glenn MorrisEmerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA; Department of Medicine, College of Medicine, Emerging Pathogens Institute, University of Florida, 2055 Mowry Road, Box 100009, Gainesville, FL 32610, USA. Electronic address: jgmorris@epi.ufl.edu.

Funding

Impact of climate on dinoflagellates and ciguatera fish poisoningU01EH000421 · EH · UNIVERSITY OF FLORIDA · PI MORRIS, JOHN GLENN · 2009 to 2011
$840k
NCEH CDC HHS U01 EH000421
6 · The paper itself

Abstract

Ciguatera fish poisoning (ciguatera) is a common clinical syndrome in areas where there is dependence on tropical reef fish for food. A subset of patients develops recurrent and, in some instances, chronic symptoms, which may result in substantial disability. To identify possible biomarkers for recurrent/chronic disease, and to explore correlations with immune gene expression, peripheral blood leukocyte gene expression in 10 ciguatera patients (7 recurrent and 3 acute) from the U.S. Virgin Islands, and 5 unexposed Florida controls were evaluated. Significant differences in gene expression were noted when comparing ciguatera patients and controls; however, it was not possible to differentiate between patients with acute and recurrent disease, possibly due to the small sample sizes involved.

Indexed as

AnimalsCiguatera PoisoningDietFishesFloridaGene ExpressionGene Expression ProfilingHumansLeukocytesUnited States Virgin IslandsCiguateraFish poisoningGene expressionU.S. Virgin Islands

Identifiers

PMID28918889
PMCPMC5008692

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.