Evidence map›Paper›PMID 28918561›Full record

ReviewArchives of pharmacal research2017

Marine polysaccharides: therapeutic efficacy and biomedical applications.

Young-Eun Lee, Hyeongmin Kim, Changwon Seo, Taejun Park, Kyung Bin Lee, Seung-Yup Yoo, Seong-Chul Hong, Jeong Tae Kim, Jaehwi Lee

Open access · bronzeAbstract readReview
In one paragraph

Review in Archives of pharmacal research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 135 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Marine biomaterials in biomedical nano/micro-systems.Journal of nanobiotechnology · 2023
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Furcellaran Surface Deposition and Its Potential in Biomedical Applications.International journal of molecular sciences · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Young-Eun LeeCollege of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, South Korea.
Hyeongmin KimCollege of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, South Korea.
Changwon SeoCollege of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, South Korea.
Taejun ParkCollege of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, South Korea.
Kyung Bin LeeCollege of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, South Korea.
Seung-Yup YooCollege of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, South Korea.
Seong-Chul HongCollege of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, South Korea.
Jeong Tae KimCollege of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, South Korea.
Jaehwi LeeCollege of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, South Korea. jaehwi@cau.ac.kr.ORCID http://orcid.org/0000-0003-3696-2626
Chung-Ang University · KR

Funding

Ministry of Health and Welfare (KR) HN13C0073National Research Foundation of Korea 2015R1A5A1008958National Research Foundation of Korea 2015R1D1A1A02062278
6 · The paper itself

Abstract

The ocean contains numerous marine organisms, including algae, animals, and plants, from which diverse marine polysaccharides with useful physicochemical and biological properties can be extracted. In particular, fucoidan, carrageenan, alginate, and chitosan have been extensively investigated in pharmaceutical and biomedical fields owing to their desirable characteristics, such as biocompatibility, biodegradability, and bioactivity. Various therapeutic efficacies of marine polysaccharides have been elucidated, including the inhibition of cancer, inflammation, and viral infection. The therapeutic activities of these polysaccharides have been demonstrated in various settings, from in vitro laboratory-scale experiments to clinical trials. In addition, marine polysaccharides have been exploited for tissue engineering, the immobilization of biomolecules, and stent coating. Their ability to detect and respond to external stimuli, such as pH, temperature, and electric fields, has enabled their use in the design of novel drug delivery systems. Thus, along with the promising characteristics of marine polysaccharides, this review will comprehensively detail their various therapeutic, biomedical, and miscellaneous applications.

Indexed as

Drug Delivery SystemsAnimalsAquatic OrganismsBiocompatible MaterialsDrug DesignHumansHydrogen-Ion ConcentrationPolysaccharidesTemperatureTissue EngineeringBiocompatible MaterialsPolysaccharidesAnti-cancerAnti-inflammatoryAnti-viralBiosensorMarine polysaccharideTissue regeneration

Identifiers

PMID28918561
PMCPMC7090684
OpenAlexW2755401791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.