Evidence map›Paper›PMID 28918515›Full record

ArticleNeurochemical research2018

Oligodendrocyte-Neuron Interactions: Impact on Myelination and Brain Function.

Takeshi Shimizu, Yasuyuki Osanai, Kazuhiro Ikenaka

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Review
  6. Value of MRS combined with DTI in evaluating brain development of infants aged from 2 months to 2 years old.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
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  12. [Neuroprotective effects of oligodendrocyte precursor cells on white matter damage in preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Takeshi ShimizuDivision of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, 5-1 Higashiyama Myodaiji, Okazaki, Aichi, 444-8787, Japan. tshimizu@med.nagoya-cu.ac.jp.
Yasuyuki OsanaiDivision of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, 5-1 Higashiyama Myodaiji, Okazaki, Aichi, 444-8787, Japan.
Kazuhiro IkenakaDivision of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, 5-1 Higashiyama Myodaiji, Okazaki, Aichi, 444-8787, Japan.
Nagoya City University · JPNational Institute for Physiological Sciences · JPThe Graduate University for Advanced Studies, SOKENDAI · JP

Funding

KAKENHI 16K14584KAKENHI 25117001
6 · The paper itself

Abstract

In the past, glial cells were considered to be 'glue' cells whose primary role was thought to be merely filling gaps in neural circuits. However, a growing number of reports have indicated the role of glial cells in higher brain function through their interaction with neurons. Myelin was originally thought to be just a sheath structure surrounding neuronal axons, but recently it has been shown that myelin exerts effects on the conduction velocity of neuronal axons even after myelin formation. Therefore, the investigation of glial cell properties and the neuron-glial interactions is important for understanding higher brain function. Moreover, since there are many neurological disorders caused by glial abnormalities, further understanding of glial cell-related diseases and the development of effective therapeutic strategies are warranted. In this review, we focused on oligodendrocyte-neuron interactions, with particular attention on (1) axonal signals underlying oligodendrocyte differentiation and myelination, (2) neuronal activity-dependent myelination and (3) the effects of myelination on higher brain function.

Indexed as

AnimalsAxonsBrainCell CommunicationCell DifferentiationMiceMyelin SheathNeurogliaNeuronsOligodendrogliaActivity-dependencyMotor skill learningMyelinationNeuronal electrical activityOligodendrocyte

Identifiers

PMID28918515
OpenAlexW2754423850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.