Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2018
Young athletes after ACL reconstruction with quadriceps strength asymmetry at the time of return-to-sport demonstrate decreased knee function 1 year later.
Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- Effects of visual feedback balance training on muscle strength and balance ability in patients after anterior cruciate ligament reconstruction surgery.BMC musculoskeletal disorders · 2026Trial
- Effects of early inertial exercises on morphological and functional recovery after ACL reconstruction.Scientific reports · 2026Trial
- Hop tests can result in higher limb symmetry index values than isokinetic strength and leg press tests in patients following ACL reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Trial
- Comparing the Effectiveness of Blood Flow Restriction and Traditional Heavy Load Resistance Training in the Post-Surgery Rehabilitation of Anterior Cruciate Ligament Reconstruction Patients: A UK National Health Service Randomised Controlled Trial.Sports medicine (Auckland, N.Z.) · 2019Trial
- The 3D Biomechanics of Secondary Non-contact ACL Injuries in Two Female Adolescents: A Case Series of an Ipsilateral ACL Re-Rupture and a Contralateral ACL Rupture.Sports medicine (Auckland, N.Z.) · 2026Article
- Factors Associated with Quadriceps Strength Recovery at 6 and 12 Months After Anterior Cruciate Ligament Reconstruction Using Quadriceps Tendon-Bone, Bone-Patellar Tendon-Bone, and Hamstring Tendon Autografts.Orthopaedic journal of sports medicine · 2026Article
- Biomechanical asymmetry during side-cutting is associated with lower limb muscle strength after anterior cruciate ligament reconstruction.BMC musculoskeletal disorders · 2026Article
- Isokinetic Quadriceps and Hamstring Peak Torque in Athletes Aged 10-50+: Preoperative Uninvolved Limb Reference Values for ACL Reconstruction.International journal of sports physical therapy · 2026Article
- The Effect of Duration of Supervised Rehabilitation on Outcomes Following Anterior Cruciate Ligament Reconstruction: A Systematic Review.International journal of sports physical therapy · 2026Article
- Inter-limb asymmetries in professional male basketball and volleyball players: bilateral vs. unilateral jump comparison.International biomechanics · 2025Article
- Blood Flow Restriction Training Prior to and After Anterior Cruciate Ligament Reconstruction: A Scoping Review.Journal of functional morphology and kinesiology · 2025Review
- Why Should Return to Sport Be Delayed by up to Two Years After ACL Reconstruction? A Narrative Review of the Biological, Surgical and Rehabilitation Evidence.Journal of clinical medicine · 2025Review
- Higher isokinetic quadriceps peak force is associated with a patient-acceptable symptom-state 1 and 3 years after ACL reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Similar strength recovery but more complications with Bone-Quadriceps Tendon Autograft compared to Quadriceps Tendon Autograft in anterior cruciate ligament reconstruction in competitive soccer players.Journal of experimental orthopaedics · 2025Article
- Comparison of Rehabilitation Characteristics Among High, Average, and Low Performers on Return-to-Sport Testing in Athletes After ACL Reconstruction.Orthopaedic journal of sports medicine · 2025Article
- Isokinetic Testing After Anterior Cruciate Ligament Injury Showed a Greater Hamstrings/Quadriceps Ratio at 240°/S Over 6 Months From Injury but No Difference of Limb Symmetry Index.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- Relationship Between Quadriceps Strength at 6 Months Postoperatively and Improvement in Patient-Reported Knee Function After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2025Article
- A novel approach to monitoring rehabilitation progress in atrophic muscle using contactless measurement of free oscillations and advanced modal analysis.Frontiers in bioengineering and biotechnology · 2025Article
- Effects of Blood Flow Restriction Training in Patients before and after Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2024Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
purposeQuadriceps femoris (QF) strength deficits at return-to-sport (RTS) after ACL reconstruction (ACLR) contribute to decreased knee function at the same time point. However, the impact of QF strength at RTS on longitudinal function has not been examined. The purpose of this study was to test the hypothesis that young athletes after ACLR with QF strength asymmetry at RTS would demonstrate decreased knee-related function and lower proportions of functional recovery at 1 year post-RTS compared to young athletes following ACLR with nearly symmetric QF strength at RTS.
methodsParticipants included 76 young athletes (74% female; mean age at RTS = 17.3 years) after primary, unilateral ACLR, cleared to RTS, and followed for 1 year after RTS. At the time of RTS, QF strength was quantified on an isokinetic dynamometer and a Limb Symmetry Index (LSI) was calculated [(involved/uninvolved) × 100%]. The cohort was subdivided into two groups based on RTS QF LSI: high quadriceps (HQ; LSI ≥ 90%; n = 36) and low quadriceps (LQ; LSI < 85%; n = 36). The cohort was followed for 1 year post-RTS, and knee-related function was assessed using the International Knee Documentation Committee subjective form (IKDC), the Knee Injury and Osteoarthritis Outcome Score (KOOS), and LSI of single-leg hop tests. Functional recovery at 1 year post-RTS was defined as KOOS scores above literature-reported cut-offs.
resultsWhile the HQ group demonstrated higher symmetry on all 1 year post-RTS hop tests, only the triple-hop test (p = 0.020) was found to be statistically different. Similarly, while the HQ group scored higher on all 1 year post-RTS self-reported knee function measures, only differences on the KOOS-Sport/Rec score (p = 0.039) and IKDC score (p = 0.011) were statistically different. Additionally, the HQ group demonstrated higher proportions of functional recovery at 1 year post-RTS than the LQ group on the KOOS-Symptoms (HQ: 88.9%, LQ: 69.4%; p = 0.040) and KOOS-Sport/Rec (HQ: 91.7%, LQ: 69.4%; p = 0.017).
conclusionsYoung athletes after ACLR with QF strength asymmetry at RTS demonstrated decreased knee-related function and lower proportions of functional recovery at 1 year post-RTS. However, group differences did not exceed reported minimal clinically important difference values. Further study is warranted to understand factors that contribute to longitudinal knee function after ACLR. Clinicians should focus on restoring symmetric QF strength at RTS after ACLR, which may promote higher longitudinal knee function. LEVEL OF EVIDENCE: Level II, Prospective cohort study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.