Evidence map›Paper›PMID 28918393›Full record

ArticleThe Journal of biological chemistry2017

Improving membrane protein expression by optimizing integration efficiency.

Michiel J M Niesen, Stephen S Marshall, Thomas F Miller, William M Clemons

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Producing membrane proteins one simulation at a time.The Journal of biological chemistry · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Michiel J M NiesenFrom the Department of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125.ORCID 0000-0002-9255-6203
Stephen S MarshallFrom the Department of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125.ORCID 0000-0003-2263-6854
Thomas F MillerFrom the Department of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125 tfm@caltech.edu.ORCID 0000-0002-1882-5380
William M ClemonsFrom the Department of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125 clemons@caltech.edu.ORCID 0000-0002-0021-889X

Funding

PREDOCTORAL TRAINING IN BIOLOGY AND CHEMISTRYT32GM007616 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI STERNBERG, PAUL WARREN · 1985 to 2019
$22.9M
NIH Pioneer AwardDP1GM105385 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI CLEMONS, WILLIAM M. · 2012 to 2015
$3.3M
A New Pradigm for the Rational Expression of Integral Membrane ProteinsR01GM125063 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI CLEMONS, WILLIAM M., MILLER, THOMAS FRANCIS · 2017 to 2020
$1.5M
NIGMS NIH HHS DP1 GM105385NIGMS NIH HHS R01 GM125063NIGMS NIH HHS T32 GM007616
6 · The paper itself

Abstract

The heterologous overexpression of integral membrane proteins in

Indexed as

Molecular Dynamics SimulationEscherichia coliEscherichia coli ProteinsLipid BilayersMembrane Transport ProteinsPoint MutationProtein BindingProtein TransportEscherichia coli ProteinsLipid BilayersMembrane Transport ProteinsTatC protein, E coliflow cytometrymembrane proteinmolecular dynamicsprotein expressionprotein translocationSec transloconTatCtopogenesis

Identifiers

PMID28918393
PMCPMC5702688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.