Evidence map›Paper›PMID 28918268›Full record

ArticlePsychiatry research. Neuroimaging2017

A structural MRI study of excoriation (skin-picking) disorder and its relationship to clinical severity.

Michael D Harries, Samuel R Chamberlain, Sarah A Redden, Brian L Odlaug, Austin W Blum, Jon E Grant

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Psychiatry research. Neuroimaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Body Focused Repetitive Behavior Disorders: Behavioral Models and Neurobiological Mechanisms.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2023
    Review
  5. Skin picking disorder: Does a person's sex matter?Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. The Role of the Cerebellum in Skin-Picking Disorder.Cerebellum (London, England) · 2019
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Michael D HarriesDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841S. Maryland Avenue, MC3077, Chicago, IL 60637, United States. Electronic address: mharries@uchicago.edu.
Samuel R ChamberlainDepartment of Psychiatry, University of Cambridge, Cambridge, United Kingdom.
Sarah A ReddenDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841S. Maryland Avenue, MC3077, Chicago, IL 60637, United States.
Brian L OdlaugFaculty of Health & Medical Sciences, University of Copenhagen, Copenhagen, Denmark; H. Lundbeck A/S, Valby, Denmark.
Austin W BlumDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841S. Maryland Avenue, MC3077, Chicago, IL 60637, United States.
Jon E GrantDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, 5841S. Maryland Avenue, MC3077, Chicago, IL 60637, United States.
University of Chicago · USUniversity of Cambridge · GBUniversity of Copenhagen · DK

Funding

Wellcome Trust 110049
6 · The paper itself

Abstract

Excoriation (skin-picking) disorder (SPD) shares symptomology with other obsessive-compulsive and related disorders. Few studies, however, have examined the neurological profile of patients with SPD. This study examined differences in cortical thickness and basal ganglia structural volumes between 20 individuals with SPD and 16 healthy controls using magnetic resonance imaging (MRI). There were no significant differences in demographic variables (age, gender, education and race) between groups. All subjects completed a structural MRI scan and completed a battery of clinical assessments focusing on SPD symptom severity, depression and anxiety symptoms, and quality of life. No statistically significant differences in basal ganglia (caudate, putamen, and nucleus accumbens) structural volumes were found between groups. In individuals with SPD, increasing impulsiveness correlated positively with increased cortical thickness in the left insula, and skin picking severity correlated negatively with cortical thickness in the left supramarginal gyrus and a region encompassing the right inferior parietal, right temporal and right supramarginal gyrus. This study suggests similarities and differences exist in symptomology between SPD and the other obsessive-compulsive and related disorders. Additional neuroimaging research is needed to better delineate the underlying neurobiology of SPD.

Indexed as

Magnetic Resonance ImagingSeverity of Illness IndexAdultBasal GangliaCerebral CortexFemaleHumansMaleMiddle AgedNucleus AccumbensQuality of LifeSelf-Injurious BehaviorSkinSoft Tissue InjuriesYoung AdultBrain imagingCortical thicknessObsessive-compulsiveSkin picking disorderStructural volume

Identifiers

PMID28918268
PMCPMC5604737
OpenAlexW2753818536

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.