ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2018
Sex Differences in Outcomes after Stroke in Patients with Diabetes in Ontario, Canada.
Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 20 citations in OpenAlex.
- Associations of Social, Behavioral, and Clinical Factors With Sex Differences in Stroke Recurrence and Poststroke Mortality.Circulation. Cardiovascular quality and outcomes · 2025Article
- Sex Difference in Capillary Reperfusion After Transient Middle Cerebral Artery Occlusion in Diabetic Mice.Stroke · 2023Article
- Sex differences in the risk of recurrent ischemic stroke after ischemic stroke and transient ischemic attack.European stroke journal · 2021Article
- Diabetes, Vascular Aging and Stroke: Old Dogs, New Tricks?Journal of clinical medicine · 2021Review
- Sex-related disparities in the incidence and outcomes of hemorrhagic stroke among type 2 diabetes patients: a propensity score matching analysis using the Spanish National Hospital Discharge Database for the period 2016-18.Cardiovascular diabetology · 2021Observational
- Sex-Related Disparities in the Incidence and Outcomes of Ischemic Stroke among Type 2 Diabetes Patients. A Matched-Pair Analysis Using the Spanish National Hospital Discharge Database for Years 2016-2018.International journal of environmental research and public health · 2021Article
- Impact of Diabetes on Complications, Long Term Mortality and Recurrence in 608,890 Hospitalised Patients with Stroke.Global heart · 2020Article
- Sex disparity in long-term stroke recurrence and mortality in a rural population in the United States.Therapeutic advances in neurological disorders · 2020Article
- Sex differences in health services and medication use among older adults with asthma.ERJ open research · 2019Article
- Long-term survival after stroke in Lithuania: Data from Kaunas population-based stroke registry.PloS one · 2019Article
- Natural language processing and machine learning algorithm to identify brain MRI reports with acute ischemic stroke.PloS one · 2019Article
- Interaction of Sex and Diabetes on Outcome After Ischemic Stroke.Frontiers in neurology · 2018Article
- Exploring Gender-Specific Stroke Risks in Diabetic Patients: Insights from a Retrospective Analysis of Contributing Factors.Iranian journal of nursing and midwifery researchArticle
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundOutcomes after stroke in those with diabetes are not well characterized, especially by sex and age. We sought to calculate the sex- and age-specific risk of cardiovascular outcomes after ischemic stroke among those with diabetes.
methodsUsing population-based demographic and administrative health-care databases in Ontario, Canada, all patients with diabetes hospitalized with index ischemic stroke between April 1, 2002, and March 31, 2012, were followed for death, stroke, and myocardial infarction (MI). The Kaplan-Meier survival analysis and Fine-Gray competing risk models estimated hazards of outcomes by sex and age, unadjusted and adjusted for demographics and vascular risk factors.
resultsAmong 25,495 diabetic patients with index ischemic stroke, the incidence of death was higher in women than in men (14.08 per 100 person-years [95% confidence interval [CI], 13.73-14.44] versus 11.89 [11.60-12.19]) but was lower after adjustment for age and other risk factors (adjusted hazard ratio [HR], .95 [.92-.99]). Recurrent stroke incidence was similar by sex, but men were more likely to be readmitted for MI (1.99 per 100 person-years [1.89-2.10] versus 1.58 [1.49-1.68] among females). In multivariable models, females had a lower risk of readmission for any event (HR, .96 [95% CI, .93-.99]).
conclusionsIn this large, population-based, retrospective study among diabetic patients with index stroke, women had a higher unadjusted death rate but lower unadjusted incidence of MI. In adjusted models, females had a lower death rate compared with males, although the increased risk of MI among males persisted. These findings confirm and quantify sex differences in outcomes after stroke in patients with diabetes.
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