ArticleCytotherapy2017
Ultrasound-assisted liposuction provides a source for functional adipose-derived stromal cells.
Article in Cytotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- FAM-Fat Augmentation Mastopexy: A Method to Avoid Implants.Aesthetic plastic surgery · 2024Article
- Augmentation-Mastopexy With 4-Layer Autologous Fat Grafting and Evaluation of Viability With MRI.Aesthetic surgery journal. Open forum · 2024Article
- Arthroscopy with Lipoaspirate and Plasma Infiltration Using Adipose-Derived Stem Cells Plus Platelet-Rich Plasma: Harvesting and Injection for Arthroscopic Treatment of Cartilage Defects of the Knee.Arthroscopy techniques · 2023Article
- Male Pectoralis Major Muscle Augmentation with Autologous Fat Transplantation Using VASER Lipoaspirate: Evaluation with MRI.Plastic and reconstructive surgery. Global open · 2023Article
- The Short-Term Effect of VASER Assisted Liposuction on Lipid Profile.Aesthetic plastic surgery · 2023Article
- The Short-Term Effect of VASER Assisted Liposuction on Lipid Profile.Aesthetic plastic surgery · 2023Article
- Adipose stem cells-derived exosomes modified gelatin sponge promotes bone regeneration.Frontiers in bioengineering and biotechnology · 2023Article
- Musculoskeletal tissue engineering: Adipose derived stromal cell implementation for the treatment of osteoarthritis.Biomaterials · 2022Review
- 1470-nm Radial fiber-assisted liposuction for body contouring and facial fat grafting.Journal of cosmetic dermatology · 2022Article
- Extracellular Vesicles of Mesenchymal Stromal Cells Can be Taken Up by Microglial Cells and Partially Prevent the Stimulation Induced by β-amyloid.Stem cell reviews and reports · 2022Article
- [Current status and prospects of clinical application of liposuction].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2022Review
- Optimization of Mesenchymal Stromal Cell (MSC) Manufacturing Processes for a Better Therapeutic Outcome.Frontiers in immunology · 2022Review
- Stem cell-based therapy for ameliorating intrauterine adhesion and endometrium injury.Stem cell research & therapy · 2021Review
- Comparison between Intra-Articular Injection of Infrapatellar Fat Pad (IPFP) Cell Concentrates and IPFP-Mesenchymal Stem Cells (MSCs) for Cartilage Defect Repair of the Knee Joint in Rabbits.Stem cells international · 2021Article
- Molecular Characterization of Lipoaspirates Used in Regenerative Head and Neck Surgery.JAMA facial plastic surgery · 2019Article
- Fibrin Glue Enhances Adipose-Derived Stromal Cell Cytokine Secretion and Survival Conferring Accelerated Diabetic Wound Healing.Stem cells international · 2018Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
Abstract
BACKGROUND
aimsRegenerative medicine employs human mesenchymal stromal cells (MSCs) for their multi-lineage plasticity and their pro-regenerative cytokine secretome. Adipose-derived mesenchymal stromal cells (ASCs) are concentrated in fat tissue, and the ease of harvest via liposuction makes them a particularly interesting cell source. However, there are various liposuction methods, and few have been assessed regarding their impact on ASC functionality. Here we study the impact of the two most popular ultrasound-assisted liposuction (UAL) devices currently in clinical use, VASER (Solta Medical) and Lysonix 3000 (Mentor) on ASCs.
methodsAfter lipoaspirate harvest and processing, we sorted for ASCs using fluorescent-assisted cell sorting based on an established surface marker profile (CD34
resultsBoth UAL samples demonstrated equivalent ASC yield and viability. VASER UAL ASCs showed higher osteogenic and adipogenic marker expression, but a comparable differentiation capacity was observed. Soft tissue healing and neovascularization were significantly enhanced via both UAL-derived ASCs in vivo, and there was no significant difference between the cell therapy groups.
conclusionsTaken together, our data suggest that UAL allows safe and efficient harvesting of the mesenchymal stromal cellular fraction of adipose tissue and that cells harvested via this approach are suitable for cell therapy and tissue engineering applications.
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