Trial reportChest2018
A Multicenter Randomized Trial of a Checklist for Endotracheal Intubation of Critically Ill Adults.
Trial report in Chest, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02497729 (Checklists and Upright Positioning in Endotracheal Intubation of Critically Ill Patients), which is not on this map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Checklists and Upright Positioning in Endotracheal Intubation of Critically Ill Patients (Check-UP) Trial
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Impact of Interventions on Peri-Intubation Hypoxemia and Hypotension in Critically Ill Patients: Systematic Review and Meta-Analysis.The western journal of emergency medicine · 2025Pooled it
- Pooled it
- Association of Checklist Use in Endotracheal Intubation With Clinically Important Outcomes: A Systematic Review and Meta-analysis.JAMA network open · 2020Pooled it
- Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials.Critical care (London, England) · 2018Pooled it
- Bag-Mask Ventilation Versus Apneic Oxygenation During Tracheal Intubation in Critically Ill Adults: A Secondary Analysis of 2 Randomized Trials.Journal of intensive care medicine · 2022Trial
- Trial
- Risk Factors for Cardiovascular Collapse during Tracheal Intubation of Critically III Adults.Annals of the American Thoracic Society · 2020Trial
- Bag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults.The New England journal of medicine · 2019Trial
- Utilization of intubation kits and checklist to improve first-pass success and reduce complications associated with endotracheal intubation in Rwanda.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2026Article
- Preoxygenation in the ICU.Journal of clinical medicine · 2025Review
- Impact of Checklist Implementation on Endotracheal Intubation-Related Complications in Critically Ill Adults-A Retrospective Before and After Study.Acta anaesthesiologica Scandinavica · 2025Observational
- Article
- Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study.Intensive care medicine · 2024Article
- Black representation in critical care randomized controlled trials: a meta-epidemiological study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Review
- Observational
- Managing the Physiologically Difficult Airway in Critically Ill Adults.Critical care (London, England) · 2023Review
- Emergency airway management in a tertiary trauma centre (AIRMAN): a one-year prospective longitudinal study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Observational
- Effect of Laryngoscope Blade Size on First Pass Success of Tracheal Intubation in Critically Ill Adults.Critical care explorations · 2023Article
- Observational
- Article
Corrections and comments
Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundHypoxemia and hypotension are common complications during endotracheal intubation of critically ill adults. Verbal performance of a written, preintubation checklist may prevent these complications. We compared a written, verbally performed, preintubation checklist with usual care regarding lowest arterial oxygen saturation or lowest systolic BP experienced by critically ill adults undergoing endotracheal intubation.
methodsA multicenter trial in which 262 adults undergoing endotracheal intubation were randomized to a written, verbally performed, preintubation checklist (checklist) or no preintubation checklist (usual care). The coprimary outcomes were lowest arterial oxygen saturation and lowest systolic BP between the time of procedural medication administration and 2 min after endotracheal intubation.
resultsThe median lowest arterial oxygen saturation was 92% (interquartile range [IQR], 79-98) in the checklist group vs 93% (IQR, 84-100) with usual care (P = .34). The median lowest systolic BP was 112 mm Hg (IQR, 94-133) in the checklist group vs 108 mm Hg (IQR, 90-132) in the usual care group (P = .61). There was no difference between the checklist and usual care in procedure duration (120 vs 118 s; P = .49), number of laryngoscopy attempts (one vs one attempt; P = .42), or severe life-threatening procedural complications (40.8% vs 32.6%; P = .20).
conclusionsThe verbal performance of a written, preprocedure checklist does not increase the lowest arterial oxygen saturation or lowest systolic BP during endotracheal intubation of critically ill adults compared with usual care. TRIAL REGISTRY: ClinicalTrials.gov; No.: NCT02497729; URL: www.clinicaltrials.gov.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.