ArticleJournal of cataract and refractive surgery2017
Efficacy of different accelerated corneal crosslinking protocols for progressive keratoconus.
Article in Journal of cataract and refractive surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Pulsed corneal crosslinking in the treatment of Keratoconus: a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Pooled it
- Transepithelial versus epithelium-off corneal crosslinking for progressive keratoconus.The Cochrane database of systematic reviews · 2021Pooled it
- The Science and Clinical Evolution of Corneal Cross-Linking: Mechanism of Action, Ultra-Structural Changes, Clinical Indications, and Emerging Treatment Strategies.Ophthalmology and therapy · 2026Review
- Corneal biomechanical and tomographic outcomes following accelerated cross-linking in keratoconus: a focus on cone localization.Japanese journal of ophthalmology · 2026Article
- The Critical Role of Oxygen Supplementation in Epithelium-On Corneal Cross-Linking: A Narrative Review.Advances in therapy · 2026Review
- Hyperbaric Oxygenation Increases Available Oxygen and Resistance to Enzymatic Digestion in Accelerated Corneal Collagen Crosslinking.Translational vision science & technology · 2025Article
- Comparison of standard versus accelerated corneal collagen cross-linking for keratoconus: 5-year outcomes from the Save Sight Keratoconus Registry.Eye (London, England) · 2024Observational
- Efficacy of customized corneal crosslinking versus standard corneal crosslinking in patients with progressive keratoconus (C-CROSS study): study protocol for a randomized controlled trial.BMC ophthalmology · 2023Article
- Demarcation Line Depth in Epithelium-Off Corneal Cross-Linking Performed at the Slit Lamp.Journal of clinical medicine · 2022Article
- Anterior pituitary, sex hormones, and keratoconus: Beyond traditional targets.Progress in retinal and eye research · 2022Article
- Long-Term Follow-Up of Combined Photorefractive Keratectomy and Corneal Crosslinking in Keratoconus Suspects.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Complications of accelerated corneal collagen cross-linking: review of 2025 eyes.International ophthalmology · 2020Article
- Simultaneous photorefractive keratectomy and accelerated collagen cross-linking in high-risk refractive surgery (Tehran protocol): 3-year outcomes.International ophthalmology · 2020Article
- Comparative 2-year outcomes of conventional and accelerated corneal collagen crosslinking in progressive keratoconus.International journal of ophthalmology · 2020Article
- Effectiveness and safety of accelerated (9 mW/cmEye (London, England) · 2019Article
- Corneal densitometry after accelerated corneal collagen cross-linking in progressive keratoconus.International ophthalmology · 2019Article
- Transepithelial accelerated versus conventional corneal collagen crosslinking in patients with keratoconus: a comparative study.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- Different accelerated corneal collagen cross-linking treatment modalities in progressive keratoconus.Eye and vision (London, England) · 2019Article
- Correlation between corneal stromal demarcation line depth and topographic outcomes after two pulsed-light-accelerated crosslinking protocols.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
Corrections and comments
- Commented on by
- Erratum issuedErratum.2017
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the efficacy of different accelerated corneal crosslinking (CXL) treatment protocols in patients with progressive keratoconus.
settingMarmara University School of Medicine, Istanbul, Turkey.
designRetrospective case series.
methodsPatients with progressive keratoconus had 9 mW accelerated CXL (10 minutes; 9 mW/cm
resultsOf 134 eyes, 34 eyes had conventional CXL, 45 had 9 mW accelerated CXL, 28 had 30 mW continuous-light accelerated CXL (4 minutes, 30 mW/cm
conclusionAlthough 30 mW accelerated CXL treatment modalities appeared to be effective in stabilizing keratoconus progression, they seemed less effective in achieving topographic improvement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.