ArticleHearing research2017
A formal description of middle ear pressure-regulation.
Article in Hearing research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed.
- "Benefits of the pedicled osteoplastic flap as a surgical approach of mastoidectomy in cochlear implant surgery".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Trial
- Assessment of the Eustachian tube: a review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Review
- CT Imaging of Eustachian Tube Balloon Dilation: Method Development on Cadaver Heads.Bioengineering (Basel, Switzerland) · 2023Article
- Article
- [The etiology and related factors of Eustachian tube dysfunction].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021Review
- Review
- Advances in Eustachian tube function testing.World journal of otorhinolaryngology - head and neck surgery · 2019Review
- Understanding Eustachian tube function.Brazilian journal of otorhinolaryngologyArticle
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
introductionMiddle ear (ME) pressure-regulation (MEPR) is a homeostatic mechanism that maintains the ME-environment pressure-gradient (MEEPG) within a range optimized for "normal" hearing.
objectiveDescribe MEPR using equations applicable to passive, inter-compartmental gas-exchange and determine if the predictions of that description include the increasing ME pressure observed under certain conditions and interpreted by some as evidencing gas-production by the ME mucosa.
methodsMEPR was modeled as the combined effect of passive gas-exchanges between the ME and: perilymph via the round window membrane, the ambient environment via the tympanic membrane, and the local blood via the ME mucosa and of gas flow between the ME and nasopharynx during Eustachian tube openings. The first 3 of these exchanges are described at the species level using the Fick's diffusion equation and the last as a bulk gas transfer governed by Poiseuille's equation. The model structure is a time-iteration of the equation: P
resultsWhen calibrated to known values, the model predicts the empirically measured ME species-pressures and the observed time-trajectories for total ME pressure and the MEEPG under a wide variety of physiologic, pathologic and non-physiologic conditions.
conclusionsPassive inter-compartmental gas exchange is sole and sufficient to describe MEPR.
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