ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019
Coronary calcium score influences referral for invasive coronary angiography after normal myocardial perfusion SPECT.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Clinical determinants of agreement and discordance between stress SPECT and invasive coronary angiography.Frontiers in cardiovascular medicine · 2026Article
- Diagnostic reference level, achievable dose, and effective dose estimation in adult hybrid SPECT myocardial perfusion imaging in Institut Jantung Negara.Scientific reports · 2025Article
- The early after discharge cardiac CT for low-risk chest pain study: the ED-CT study.The British journal of radiology · 2024Article
- How will lung cancer screening and lung nodule management change the diagnostic and surgical lung cancer landscape?European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Machine learning based model to diagnose obstructive coronary artery disease using calcium scoring, PET imaging, and clinical data.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- The impact of coronary calcium score as an addition to myocardial perfusion imaging in altering clinical management (ICCAMPA trial).Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Clinical Application of Myocardial Perfusion SPECT in Patients with Suspected or Known Coronary Artery Disease. What Role in the Multimodality Imaging Era?Reviews in cardiovascular medicine · 2023Review
- Diagnostic value of regional myocardial flow reserve measurements using Rubidium-82 PET : Disclosures none.The international journal of cardiovascular imaging · 2022Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2019: Positron emission tomography, computed tomography and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Review
- Use of coronary artery calcium scanning as a triage for invasive coronary angiography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Impact of coronary artery calcium testing on patient management.Journal of cardiovascular computed tomographyArticle
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7 authors.
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Abstract
backgroundIn patients with normal SPECT but persistent complaints, invasive angiography may exclude obstructive coronary disease. We assessed whether high coronary artery calcium (CAC) scores are associated with increased referral for invasive angiography following normal SPECT. METHODS AND
results2286 consecutive patients (mean age 60 ± 12, 39% male) with normal SPECT were assessed. All patients underwent simultaneous CAC scoring. Patients were categorized into four groups based on their CAC score: CAC = 0 (n = 694), CAC 1 to 100 (n = 891), CAC 101 to 400 (n = 368), and CAC >400 (n = 333). The decision to perform angiography was left to the discretion of treating physician. Follow-up angiography was confined to the first 60 days after SPECT. Occurrence of MACE (late revascularization, myocardial infarction or death) was recorded. Overall, 100 patients (4.4%) underwent early angiography with increasing rates in higher CAC score groups (1.0%, 2.6%, 8.4%, and 11.7%), respectively, P < .001). A CAC score >400 (OR 3.56, 95% CI 2.19 to 5.77, P < .001) was independently associated with referral to angiography. Similarly, CAC score >400 was an independent predictor for MACE (HR 9.26, 95% CI 5.06 to 16.93). Early angiography did not influence prognosis (HR 1.57, 95% CI 0.91 to 2.73).
conclusionsCAC scoring impacts clinical decision-making and increases referral rates for invasive angiography after normal SPECT.
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