ArticleScientific reports2017
Chronic interfacing with the autonomic nervous system using carbon nanotube (CNT) yarn electrodes.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Scaling beyond the vagus nerve: historical and contemporary progress on electrode-based small-diameter peripheral nerve interfaces.Bioelectronic medicine · 2026Review
- Materials and System Design for Self-Decision Bioelectronic Systems.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Bradycardia is induced by hyperactivity of the vagus nerve and nucleus ambiguus during seizures propagating into the brainstem.Epilepsia open · 2025Article
- Accessing the viscera: Technologies for interoception research.Current opinion in neurobiology · 2025Review
- Functional Nanomaterials for Advanced Bioelectrode Interfaces: Recent Advances in Disease Detection and Metabolic Monitoring.Sensors (Basel, Switzerland) · 2025Review
- Effect of Anesthesia and Diurnal Variation on Chronic Vagus Nerve Activity in Rats.Journal of neuroscience research · 2025Article
- Computational models of compound nerve action potentials: Efficient filter-based methods to quantify effects of tissue conductivities, conduction distance, and nerve fiber parameters.PLoS computational biology · 2024Article
- Selective chronic recording in small nerve fascicles of sciatic nerve with carbon nanotube yarns in rats.Journal of neural engineering · 2024Article
- Vagus nerve electroneurogram-based detection of acute kainic acid induced seizures.Frontiers in neuroscience · 2024Article
- Bioelectronic Medicine: a multidisciplinary roadmap from biophysics to precision therapies.Frontiers in integrative neuroscience · 2024Review
- Fabrication and Validation of Sub-Cellular Carbon Fiber Electrodes.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024Article
- Sports Participation and Academic Performance in Primary School: A Cross-Sectional Study in Chinese Children.International journal of environmental research and public health · 2023Article
- Recent developments in multifunctional neural probes for simultaneous neural recording and modulation.Microsystems & nanoengineering · 2023Review
- Implantable intracortical microelectrodes: reviewing the present with a focus on the future.Microsystems & nanoengineering · 2023Review
- Ultraflexible and Stretchable Intrafascicular Peripheral Nerve Recording Device with Axon-Dimension, Cuff-Less Microneedle Electrode Array.Small (Weinheim an der Bergstrasse, Germany) · 2022Article
- Flexible Electronics and Devices as Human-Machine Interfaces for Medical Robotics.Advanced materials (Deerfield Beach, Fla.) · 2022Review
- Decoding Vagus-Nerve Activity with Carbon Nanotube Sensors in Freely Moving Rodents.Biosensors · 2022Article
- A flexible protruding microelectrode array for neural interfacing in bioelectronic medicine.Microsystems & nanoengineering · 2022Article
- A system of real-time neural recording and stimulation and its potential application in blood pressure modulation.Frontiers in medical technology · 2022Article
- Carbon fiber electrodes for intracellular recording and stimulation.Journal of neural engineering · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The ability to reliably and safely communicate chronically with small diameter (100-300 µm) autonomic nerves could have a significant impact in fundamental biomedical research and clinical applications. However, this ability has remained elusive with existing neural interface technologies. Here we show a new chronic nerve interface using highly flexible materials with axon-like dimensions. The interface was implemented with carbon nanotube (CNT) yarn electrodes to chronically record neural activity from two separate autonomic nerves: the glossopharyngeal and vagus nerves. The recorded neural signals maintain a high signal-to-noise ratio (>10 dB) in chronic implant models. We further demonstrate the ability to process the neural activity to detect hypoxic and gastric extension events from the glossopharyngeal and vagus nerves, respectively. These results establish a novel, chronic platform neural interfacing technique with the autonomic nervous system and demonstrate the possibility of regulating internal organ function, leading to new bioelectronic therapies and patient health monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.