Evidence map›Paper›PMID 28916724›Full record

ArticleThe Journal of biological chemistry2017

A novel mechanism for Ca

Xiaohan Wang, Christian R Marks, Tyler L Perfitt, Terunaga Nakagawa, Amy Lee, David A Jacobson, Roger J Colbran

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Synapse-to-Nucleus ERK→CREB Transcriptional Signaling Requires Dendrite-to-Soma CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Clustering of CaJournal of neurochemistry · 2023
    Article
  8. Review
  9. Role of CaFrontiers in molecular neuroscience · 2022
    Review
  10. Functional implications of CaMKII alternative splicing.The European journal of neuroscience · 2021
    Review
  11. Article
  12. Article
  13. CaThe Journal of biological chemistry · 2020
    Article
  14. Article
  15. Article
  16. Review
  17. Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  18. Genetic silencing of striatal CaV1.3 prevents and ameliorates levodopa dyskinesia.Movement disorders : official journal of the Movement Disorder Society · 2019
    Article
  19. Activated CaMKIIMolecular pharmacology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xiaohan WangFrom the Vanderbilt Brain Institute.ORCID 0000-0001-7895-2333
Christian R Marksthe Department of Molecular Physiology and Biophysics, and.
Tyler L Perfittthe Department of Molecular Physiology and Biophysics, and.
Terunaga NakagawaFrom the Vanderbilt Brain Institute.ORCID 0000-0001-6174-5012
Amy Leethe Departments of Molecular Physiology and Biophysics, Otolaryngology Head-Neck Surgery, and Neurology, University of Iowa, Iowa City, Iowa 52242.
David A Jacobsonthe Department of Molecular Physiology and Biophysics, and.ORCID 0000-0003-1816-5375
Roger J ColbranFrom the Vanderbilt Brain Institute, roger.colbran@vanderbilt.edu.ORCID 0000-0001-7401-8244
Allen Institute for Brain Science · USInstitute of Molecular Biology and Biophysics · RUUniversity of Iowa · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
TRANSGENIC MOUSE/ ES CELL SHARES RESOURCESP60DK020593 · NIDDK · VANDERBILT UNIVERSITY · PI MCGUINNESS, OWEN P · 1986 to 2011
$28.1M
Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 1989 to 2026
$19.6M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Vanderbilt Mouse Metabolic Phenotyping CenterU2CDK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2016 to 2021
$6.3M
Mechanisms of CaM Kinase II Signal TransductionR01MH063232 · NIMH · VANDERBILT UNIVERSITY · PI COLBRAN, ROGER J · 2001 to 2015
$5.4M
Regulation of auditory calcium channelsR01DC009433 · NIDCD · UNIVERSITY OF IOWA · PI LEE, AMY · 2009 to 2018
$3.6M
Two-Pore-Domain Potassium Channels as Novel Targets for Modulating Islet Hormone SecretionR01DK097392 · NIDDK · VANDERBILT UNIVERSITY · PI JACOBSON, DAVID AARON · 2013 to 2022
$3.3M
Regulation of Neuronal Calcium ChannelsR01NS084190 · NINDS · UNIVERSITY OF IOWA · PI LEE, AMY · 2014 to 2018
$2.2M
NCI NIH HHS P30 CA068485NEI NIH HHS P30 EY008126NICHD NIH HHS R01 HD061543NICHD NIH HHS U54 HD083211NIDCD NIH HHS R01 DC009433NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS P60 DK020593NIDDK NIH HHS R01 DK097392NIDDK NIH HHS U24 DK059637NIDDK NIH HHS U2C DK059637NIMH NIH HHS F31 MH109196NIMH NIH HHS R01 MH063232NINDS NIH HHS R01 NS078291NINDS NIH HHS R01 NS084190
6 · The paper itself

Abstract

Neuronal excitation can induce new mRNA transcription, a phenomenon called excitation-transcription (E-T) coupling. Among several pathways implicated in E-T coupling, activation of voltage-gated L-type Ca

Indexed as

AnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium ChannelsCell NucleusFemaleHippocampusLearningMemoryNeuronsProtein DomainsRatsRats, Sprague-DawleySignal TransductionCacna1d protein, ratCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium ChannelsCa2+/calmodulin-dependent protein kinase II (CaMKII)calcium channelcAMP-response element-binding protein (CREB)neuronprotein-protein interaction

Identifiers

PMID28916724
PMCPMC5655510
OpenAlexW2753973256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.