Evidence map›Paper›PMID 28916654›Full record

ArticleCancer research2017

Biallelic

Jason A Hanna, Catherine J Drummond, Matthew R Garcia, Jonathan C Go, David Finkelstein, Jerold E Rehg, Mark E Hatley

Open access · greenAbstract read
In one paragraph

Article in Cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. ADAM19: biological characteristics and implications in disease pathology and clinical applications.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Cells · 2025
    Article
  6. Article
  7. Review
  8. miR-497 Target Gene Regulatory Network in Angiosarcoma.Molecular cancer research : MCR · 2024
    Article
  9. Review
  10. Target gene regulatory network of miR-497 in angiosarcoma.bioRxiv : the preprint server for biology · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jason A HannaDepartment of Oncology, Molecular Oncology Division, St. Jude Children's Research Hospital, Memphis, Tennessee.
Catherine J DrummondDepartment of Oncology, Molecular Oncology Division, St. Jude Children's Research Hospital, Memphis, Tennessee.
Matthew R GarciaDepartment of Oncology, Molecular Oncology Division, St. Jude Children's Research Hospital, Memphis, Tennessee.
Jonathan C GoDepartment of Oncology, Molecular Oncology Division, St. Jude Children's Research Hospital, Memphis, Tennessee.
David FinkelsteinDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Jerold E RehgDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Mark E HatleyDepartment of Oncology, Molecular Oncology Division, St. Jude Children's Research Hospital, Memphis, Tennessee. mark.hatley@stjude.org.
St. Jude Children's Research Hospital · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Defining the non-myogenic origins of pediatric rhabdomyosarcomaR01CA216344 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HATLEY, MARK EDWARD · 2017 to 2021
$2.0M
Dissection of microRNA-21s role in non-small cell lung cancerK08CA151649 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HATLEY, MARK EDWARD · 2011 to 2015
$842k
NCI NIH HHS K08 CA151649NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA216344
6 · The paper itself

Abstract

Angiosarcoma is an aggressive vascular sarcoma with an extremely poor prognosis. Because of the relative rarity of this disease, its molecular drivers and optimal treatment strategies are obscure. DICER1 is an RNase III endoribonuclease central to miRNA biogenesis, and germline

Indexed as

MutationAnimalsDEAD-box RNA HelicasesGene Expression ProfilingGene Expression Regulation, NeoplasticGenes, Tumor SuppressorGenetic Predisposition to DiseaseHemangiosarcomaHomozygoteHumansKaplan-Meier EstimateMice, KnockoutMice, TransgenicMicroRNAsRibonuclease IIIDEAD-box RNA HelicasesDICER1 protein, humanDicer1 protein, mouseMicroRNAsMIRN23a microRNA, humanMirn23b microRNA, mouseRibonuclease III

Identifiers

PMID28916654
PMCPMC5708169
OpenAlexW2755579458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.