Evidence map›Paper›PMID 28916539›Full record

ArticleGenome research2017

Comparative analysis of alternative polyadenylation in

Xiaochuan Liu, Mainul Hoque, Marc Larochelle, Jean-François Lemay, Nathan Yurko, James L Manley, François Bachand, Bin Tian

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Genome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 58 citations in OpenAlex.

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  9. Light regulates widespread plant alternative polyadenylation through the chloroplast.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Xiaochuan LiuDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, USA.
Mainul HoqueDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, USA.
Marc LarochelleRNA Group, Department of Biochemistry, Université de Sherbrooke, Sherbrooke, Quebec J1E 4K8, Canada.
Jean-François LemayRNA Group, Department of Biochemistry, Université de Sherbrooke, Sherbrooke, Quebec J1E 4K8, Canada.
Nathan YurkoDepartment of Biological Sciences, Columbia University, New York, New York 10027, USA.
James L ManleyDepartment of Biological Sciences, Columbia University, New York, New York 10027, USA.
François BachandRNA Group, Department of Biochemistry, Université de Sherbrooke, Sherbrooke, Quebec J1E 4K8, Canada.
Bin TianDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, USA.
Rutgers, The State University of New Jersey · USUniversité de Sherbrooke · CAColumbia University · US

Funding

Regulation of RNA processing: Mechanisms and ConsequencesR35GM118136 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI James L. Manley · 2016 to 2026
$8.9M
Regulation of Alternative Cleavage and PolyadenylationR01GM084089 · NIGMS · WISTAR INSTITUTE · PI TIAN, BIN · 2008 to 2023
$6.7M
CELLULAR AND MOLECULAR FOUNDATIONS OF BIOMEDICAL SCIENCET32GM008798 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI PRYWES, RON M · 2001 to 2018
$6.3M
Illumina NextSeq500 DNA Sequencing SystemS10OD018206 · OD · RBHS-NEW JERSEY MEDICAL SCHOOL · PI TIAN, BIN · 2015 to 2015
$227k
CIHR MOP-106595NIGMS NIH HHS R01 GM084089NIGMS NIH HHS R35 GM118136NIGMS NIH HHS T32 GM008798NIH HHS S10 OD018206
6 · The paper itself

Abstract

Alternative polyadenylation (APA) is a widespread mechanism that generates mRNA isoforms with distinct properties. Here we have systematically mapped and compared cleavage and polyadenylation sites (PASs) in two yeast species,

Indexed as

3' Untranslated RegionsGene Expression Regulation, FungalNucleotide MotifsPolyadenylationRNA, FungalSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSchizosaccharomycesSchizosaccharomyces pombe Proteins3' Untranslated RegionsRNA, FungalSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe Proteins

Identifiers

PMID28916539
PMCPMC5630032
OpenAlexW2756394339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.