Evidence map›Paper›PMID 28915919›Full record

Trial reportBMC public health2017

Project LifeSkills - a randomized controlled efficacy trial of a culturally tailored, empowerment-based, and group-delivered HIV prevention intervention for young transgender women: study protocol.

Lisa M Kuhns, Matthew J Mimiaga, Sari L Reisner, Katie Biello, Robert Garofalo

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01575938 (HIV Prevention Intervention for Young Transgender Women), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01575938 nacompletednot on this map

HIV Prevention Intervention for Young Transgender Women

TypeinterventionalSponsorAnn & Robert H Lurie Children's Hospital of ChicagoRan2012 to 2016Enrolled300ConditionsSexual Transmission of InfectionArmsHIV prevention intervention, Diet and Nutrition
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Transgender Individuals and Digital Health.Current HIV/AIDS reports · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lisa M KuhnsDivision of Adolescent Medicine, Ann & Robert H. Lurie Children's Hospital, 225 E. Chicago Avenue, Box 161, Chicago, IL, 60611, USA. lkuhns@luriechildrens.org.ORCID 0000-0001-8294-7801
Matthew J MimiagaThe Fenway Institute, Fenway Health, Boston, MA, USA.
Sari L ReisnerThe Fenway Institute, Fenway Health, Boston, MA, USA.
Katie BielloThe Fenway Institute, Fenway Health, Boston, MA, USA.
Robert GarofaloDivision of Adolescent Medicine, Ann & Robert H. Lurie Children's Hospital, 225 E. Chicago Avenue, Box 161, Chicago, IL, 60611, USA.
Brown University · USNorthwestern University · USBoston Children's Hospital · US

Funding

HIV Prevention Intervention for Young Transgender WomenR01MH094323 · NIMH · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI GAROFALO, ROBERT, MIMIAGA, MATTHEW JAMES · 2011 to 2015
$3.7M
NIMH NIH HHS R01 MH094323
6 · The paper itself

Abstract

backgroundTransgender women in the U.S. have an alarmingly high incidence rate of HIV infection; condomless anal and vaginal sex is the primary risk behavior driving transmission. Young transgender women are the subpopulation at the highest risk for HIV. Despite this, there are no published randomized controlled efficacy trials testing interventions to reduce sexual risk for HIV among this group. This paper describes the design of a group-based intervention trial to reduce sexual risk for HIV acquisition and transmission in young transgender women.

methodsThis study, funded by the National Institutes of Health, is a randomized controlled trial of a culturally-specific, empowerment-based, and group-delivered six-session HIV prevention intervention, Project LifeSkills, among sexually active young transgender women, ages 16-29 years in Boston and Chicago. Participants are randomized (2:2:1) to either the LifeSkills intervention, standard of care only, or a diet and nutrition time- and attention-matched control. At enrollment, all participants receive standardized HIV pre- and post-test counseling and screening for HIV and urogenital gonorrhea and chlamydia infections. The primary outcome is difference in the rate of change in the number of self-reported condomless anal or vaginal sex acts during the prior 4-months, assessed at baseline, 4-, 8-, and 12-month follow-up visits. DISCUSSION: Behavioral interventions to reduce sexual risk for HIV acquisition and transmission are sorely needed for young transgender women. This study will provide evidence to determine feasibility and efficacy in one of the first rigorously designed trials for this population.

trial registrationClinicalTrials.gov number, NCT01575938 , registered March 29, 2012.

Indexed as

Cultural CompetencyPower, PsychologicalAdolescentAdultBostonChicagoFeasibility StudiesFemaleFollow-Up StudiesHealth Risk BehaviorsHIV InfectionsHumansMalePsychotherapy, GroupSexual BehaviorTransgender PersonsHIV preventionInterventionTransgender women

Identifiers

PMID28915919
PMCPMC5603056
OpenAlexW2755813353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.