Evidence map›Paper›PMID 28915904›Full record

Trial reportTrials2017

TIGA-CUB - manualised psychoanalytic child psychotherapy versus treatment as usual for children aged 5-11 years with treatment-resistant conduct disorders and their primary carers: study protocol for a randomised controlled feasibility trial.

Elizabeth Edginton, Rebecca Walwyn, Kayleigh Burton, Robert Cicero, Liz Graham, Sadie Reed, Sandy Tubeuf, Maureen Twiddy, Alex Wright-Hughes, Lynda Ellis and 5 more

Open access · goldAbstract readMulticenter StudyPragmatic Clinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Elizabeth EdgintonChild Oriented Mental health Interventions Centre (COMIC), Leeds and York Partnership NHS Foundation Trust, University of York, IT Building, Innovation Way, York, YO10 5NP, UK. elizabeth.edginton@nhs.net.ORCID 0000-0001-7997-5035
Rebecca WalwynLeeds Clinical Trials Research Unit, University of Leeds, Leeds, UK.
Kayleigh BurtonLeeds Clinical Trials Research Unit, University of Leeds, Leeds, UK.
Robert CiceroLeeds Clinical Trials Research Unit, University of Leeds, Leeds, UK.
Liz GrahamLeeds Clinical Trials Research Unit, University of Leeds, Leeds, UK.
Sadie ReedLeeds Clinical Trials Research Unit, University of Leeds, Leeds, UK.
Sandy TubeufLeeds Institute of Health Sciences, University of Leeds, Leeds, UK.
Maureen TwiddyLeeds Institute of Health Sciences, University of Leeds, Leeds, UK.
Alex Wright-HughesLeeds Clinical Trials Research Unit, University of Leeds, Leeds, UK.
Lynda EllisNorthern School of Child and Adolescent Psychotherapy (NSCAP), Leeds and York Partnership NHS Foundation Trust, Leeds, UK.
Dot EvansCity of York Council, York, UK.
Tom HughesGeneral Adult Psychiatry, Leeds and York Partnership NHS Foundation Trust, Leeds, UK.
Nick MidgleyChild Attachment and Psychological Therapies Research Unit (ChAPTRe), Anna Freud National Centre for Children and Families, London, UK.
Paul WallisThe Winnicott Centre, CAMHS Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
David CottrellLeeds Institute of Health Sciences, University of Leeds, Leeds, UK.
University of Leeds · GBLeeds and York Partnership NHS Foundation Trust · GBAnna Freud Centre · GBCity of York Council · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe National Institute for Health and Care Excellence (NICE) recommends evidence-based parenting programmes as a first-line intervention for conduct disorders (CD) in children aged 5-11 years. As these are not effective in 25-33% of cases, NICE has requested research into second-line interventions. Child and Adolescent Psychotherapists (CAPTs) address highly complex problems where first-line treatments have failed and there have been small-scale studies of Psychoanalytic Child Psychotherapy (PCP) for CD. A feasibility trial is needed to determine whether a confirmatory trial of manualised PCP (mPCP) versus Treatment as Usual (TaU) for CD is practicable or needs refinement. The aim of this paper is to publish the abridged protocol of this feasibility trial. METHODS AND

designTIGA-CUB (Trial on improving Inter-Generational Attachment for Children Undergoing Behaviour problems) is a two-arm, pragmatic, parallel-group, multicentre, individually randomised (1:1) controlled feasibility trial (target n = 60) with blinded outcome assessment (at 4 and 8 months), which aims to develop an optimum practicable protocol for a confirmatory, pragmatic, randomised controlled trial (RCT) (primary outcome: child's behaviour; secondary outcomes: parental reflective functioning and mental health, child and parent quality of life), comparing mPCP and TaU as second-line treatments for children aged 5-11 years with treatment-resistant CD and inter-generational attachment difficulties, and for their primary carers. Child-primary carer dyads will be recruited following a referral to, or re-referral within, National Health Service (NHS) Child and Adolescent Mental Health Services (CAMHS) after an unsuccessful first-line parenting intervention. PCP will be delivered by qualified CAPTs working in routine NHS clinical practice, using a trial-specific PCP manual (a brief version of established PCP clinical practice). Outcomes are: (1) feasibility of recruitment methods, (2) uptake and follow-up rates, (3) therapeutic delivery, treatment retention and attendance, intervention adherence rates, (4) follow-up data collection, and (5) statistical, health economics, process evaluation, and qualitative outcomes. DISCUSSION: TIGA-CUB will provide important information on the feasibility and potential challenges of undertaking a confirmatory RCT to evaluate the effectiveness and cost-effectiveness of mPCP.

trial registrationCurrent Controlled Trials, ID: ISRCTN86725795 . Registered on 31 May 2016.

Indexed as

Child BehaviorAge FactorsCaregiversChildChild, PreschoolClinical ProtocolsConduct DisorderCost-Benefit AnalysisEnglandFeasibility StudiesFemaleHealth Care CostsHumansIntergenerational RelationsMaleMental HealthConduct disordersInter-generational attachmentPsychoanalytic child psychotherapyRandomised controlled trialTreatment-resistant

Identifiers

PMID28915904
PMCPMC5602865
OpenAlexW2755263779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.