Evidence map›Paper›PMID 28915849›Full record

ArticleBMC infectious diseases2017

Exposure rate of VZV among women attending antenatal care clinic in Sri Lanka - a cross sectional study.

Saluwadana Walawwe Pavithra Lakmini Daulagala, Faseeha Noordeen, Mohamed Mukthar Fathina Fara, Chathura Rathnayake, Kapila Gunawardana

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Saluwadana Walawwe Pavithra Lakmini DaulagalaDepartment of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Faseeha NoordeenDepartment of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka. faseeha.noordeen12@gmail.com.ORCID 0000-0002-2018-0606
Mohamed Mukthar Fathina FaraDepartment of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Chathura RathnayakeDepartment of Gynecology and Obstetrics, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Kapila GunawardanaDepartment of Gynecology and Obstetrics, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
University of Peradeniya · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVaricella or chickenpox was not a notifiable disease until 2005 in Sri Lanka and only a few studies have been conducted on the epidemiology of VZV infection in the country. The anti-VZV IgG sero-prevalence among antenatal women is extremely limited and thus a selected group of antenatal clinic attendees were chosen to determine the exposure rate to VZV infection.

methodsWomen attending the antenatal clinic at Teaching Hospital, Peradeniya, Sri Lanka were selected for the study and 3 mL of venous blood was collected from 181 participants and the demographic data was obtained through a pre-tested questionnaire. Sera of the women were then tested for the presence of anti-VZV IgG using ELISA (HUMAN Diagnostics, Germany). Data was analysed using the SPSS statistical software for Windows, Version 12.0.

resultsOf the 181 antenatal women who took part in the study, 141 were positive for anti-VZV IgG giving a sero-prevalence of 77.9% for the past exposure to VZV. Of the 141 anti-VZV IgG positive women, 43.3% (n = 61) were from urban, 41.8% (n = 59) were from rural and 14.9% (n = 21) were from estate populations (an ethnic population living in small settlements in the tea estates whose ancestors were brought from India during the British colonial period to work in the tea plantations in Sri Lanka). Out of the 88 antenatal women with a positive history for varicella, 85 (96.6%) were positive for anti-VZV IgG. The highest number of anti-VZV IgG positivity was seen in the 31-35 age group, which was 85.0% of the total number of antenatal women included in that category. An increase in the anti-VZV IgG sero-prevalence with increasing age was also noted in the study sample.

conclusionExposure rate of VZV infection as confirmed by anti-VZV IgG in the present study sample of antenatal women was 77.9%. Age specific, population based future sero-prevalence studies should be conducted in Sri Lanka to understand the anti-VZV IgG status in the country.

Indexed as

AdolescentAdultAmbulatory Care FacilitiesChickenpoxCross-Sectional StudiesFemaleHerpesvirus 3, HumanHumansIndiaMiddle AgedPregnancyPrenatal CareRural PopulationSri LankaUrban PopulationVaricella Zoster Virus InfectionAntenatalAnti-VZV IgGEpidemiologySero-prevalenceSri LankaVaricella

Identifiers

PMID28915849
PMCPMC5602960
OpenAlexW2754372178

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.