ArticleBMC cardiovascular disorders2017
Anemia in severe heart failure patients: does it predict prognosis?
Article in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of the prevalence and predictors of anemia among children in Ethiopia.African health sciences · 2020Pooled it
- Prevalence of anemia in adult heart failure patients at Saint Paul's hospital millennium medical college and Saint Peter's speialized hospital in Addis Ababa Ethiopia: a cross sectional study.BMC cardiovascular disorders · 2026Article
- Time to Mortality and Predictive Factors Among Adult Heart Failure Patients: Lessons From a Resource-Limited Setting.Cardiology research and practice · 2025Article
- The Predictive Value of Hemoglobin to Red Cell Blood Distribution Width Ratio Combined with Serum Sodium for MACE of Acute Heart Failure with Preserved Ejection Fraction in Elderly Patients.International journal of general medicine · 2024Article
- The Interplay of Comorbidities in Chronic Heart Failure: Challenges and Solutions.Current cardiology reviews · 2024Review
- Structural Model of Biomedical and Contextual Factors Predicting In-Hospital Mortality due to Heart Failure.Journal of personalized medicine · 2023Article
- Anaemia and Congestion in Heart Failure: Correlations and Prognostic Role.Biomedicines · 2023Article
- Comparison of the red blood cell indices based on accuracy, sensitivity, and specificity to predict one-year mortality in heart failure patients.BMC cardiovascular disorders · 2022Article
- The cardiosplenic axis: the prognostic role of the spleen in heart failure.Heart failure reviews · 2022Review
- Time to Death and Its Determinant Factors Among Patients With Chronic Heart Failure in Northwest Ethiopia: A Retrospective Study at Selected Referral Hospitals.Frontiers in cardiovascular medicine · 2022Article
- Article
- Cardiac Diagnostic Feature and Demographic Identification (CDF-DI): An IoT Enabled Healthcare Framework Using Machine Learning.Sensors (Basel, Switzerland) · 2021Article
- Heart failure care and outcomes in a Tanzanian emergency department: A prospective observational study.PloS one · 2021Observational
- The association of anemia as a risk of heart failure.Journal of family medicine and primary care · 2020Article
- Prediction of cardiac events using fully automated GLS and BNP titers in patients with known or suspected heart failure.PloS one · 2020Article
- Association between Anemia and Cognitive Impairment among Elderly Patients with Heart Failure.International journal of environmental research and public health · 2019Article
- Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAnemia is highly prevalent in heart failure (HF) patients. However, the prevalence, clinical impact and prognostic factor of anemia in heart failure patients is widely varies. The aim of this study was to evaluate the prevalence of anemia in patients with HF, to compare baseline clinical characteristic and outcomes of severe HF patients with and without anemia admitted to Gondar University Referral Hospital (GURH), Gondar, Ethiopia.
methodA retrospective cohort study was conducted and we assessed medical records of heart failure patients who were admitted Gondar University Referral Hospital in the period between December 02, 2010 and November 30, 2016. Kaplan Meier curve was used to analyze the survival status and log rank test was used to compare the curves. Multivariate Cox regression was used to analyze independent predictors of mortality in all HF patients. P value less than 0.05 was considered statistically significant.
resultThree hundred and seventy patients participated in the study. The prevalence of anemia in the study cohorts was 41.90% and majority of the participants were females (64.59%). There was a significant difference in the level of hemoglobin, creatinine, and sodium among anemic and non-anemic patients. Anemic patients with HF tend to take angiotensin converting enzyme inhibitors (ACEI) less frequently. Kaplan Meier survival curves and Log rank test (P = 0.042) showed a significant difference in the prognosis of HF patients with anemia and non - anemic. More significant difference was observed (Log rank test, P = 0.001) in the study participants based on hemoglobin level. Furthermore, multivariate Cox regression showed: advanced age, levels of lower sodium and higher creatinine, and absences of medications like ACEI and Spironolactone independently predicted overall mortality.
conclusionHF patients with anemia tend to be older age, had lower hemoglobin and sodium level and higher creatinine value. Moreover, there was a significant difference in the prognosis between study cohorts, as anemic pateints tend to have a worse survival status . Even though, anemia is a significant risk marker, it is not an independent predictor of mortality in the current study.
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