ArticleBMC ophthalmology2017
Macular retinal and choroidal thickness in unilateral amblyopia using swept-source optical coherence tomography.
Article in BMC ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Analysis of retina, choroid, and microvascular structures in amblyopic patients using OCT and OCTA.BMC ophthalmology · 2026Article
- OCT Assessment of Deep Optic Nerve Head, Subfoveal Choroidal Thickness, and Retinal Layers in Unilateral Anisometropic Amblyopia.Beyoglu eye journal · 2026Article
- Exploration of the Value of Optical Coherence Tomography (OCT) and OCT Angiography in Differentiating Between Major Depressive Disorder and Borderline Personality Disorder.International journal of methods in psychiatric research · 2025Article
- Understanding amblyopia from the perspective of neurovascular units: changes in the retina and brain.Frontiers in cell and developmental biology · 2025Review
- Assessment of macular choroidal and retinal thickness: a cohort study in Tibetan healthy children.Scientific reports · 2024Article
- Impact of transcranial Direct Current Stimulation on stereoscopic vision and retinal structure in adult amblyopic rodents.Eye and brain · 2024Article
- Microvasculature evaluation of anisometropic amblyopia children by Angio-OCT.Scientific reports · 2023Article
- Evaluation of Choroidal Vascular Structure in Hyperopic Anisometropic Amblyopia.Beyoglu eye journal · 2023Article
- Evaluation of Macular Ganglion Cell-Inner Plexiform Layer in Children with Deprivational Amblyopia Who Underwent Unilateral Cataract Surgery.Medicina (Kaunas, Lithuania) · 2022Article
- Retinal nerve fiber layer thickness in amblyopia.Indian journal of ophthalmology · 2022Article
- Evaluation of Choroidal Vascular Index in Amblyopic Patients.Turkish journal of ophthalmology · 2022Article
- Examination of Macular Retina and Choroidal Thickness in High Myopic Amblyopia Using Spectral-Domain Optical Coherence Tomography.Frontiers in medicine · 2022Article
- Analysis of Macular Retinal Thickness and Microvascular System Changes in Children with Monocular Hyperopic Anisometropia and Severe Amblyopia.Disease markers · 2022Article
- Macular Microvasculature and Associated Retinal Layer Thickness in Pediatric Amblyopia: Magnification-Corrected Analyses.Investigative ophthalmology & visual science · 2021Article
- Choroidal and Macular Thickness in Eyes with Amblyopia.Beyoglu eye journal · 2021Article
- Choroidal vessel density in unilateral hyperopic amblyopia using en-face optical coherence tomography.BMC ophthalmology · 2020Article
- Topographic distribution features of the choroidal and retinal nerve fiber layer thickness in Wenzhou school-aged children.International journal of ophthalmology · 2020Article
- Topographic distribution features of the choroidal and retinal nerve fiber layer thickness in Chinese school-aged children.International journal of ophthalmology · 2020Article
- Effect of optical correction on choroidal structure in children with anisohypermetropic amblyopia.PloS one · 2020Article
- Analysis of retinal nerve fiber layer thickness in anisometropic amblyopia via optic coherence tomography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
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Authors and funding
9 authors.
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Abstract
backgroundTo investigate macular retinal and choroidal thickness in amblyopic eyes compared to that in fellow and normal eyes using swept-source optical coherence tomography (SS-OCT).
methodsThis study examined 31 patients with hyperopic anisometropic amblyopia (6.9 ± 3.8 years, mean ± standard deviation), 15 patients with strabismic amblyopia without anisometropia (7.9 ± 4.2 years), and 24 age-matched controls (7.8 ± 3.3 years). Retinal and choroidal thickness was measured by 3D scans using SS-OCT. A 6-mm area around the fovea was automatically analyzed using the Early Treatment Diabetic Retinopathy Study map. The thickness from SS-OCT was corrected for magnification error using individual axial length, spherical refraction, cylinder refraction, and corneal radius. Retinal thickness was divided into the macular retinal nerve fiber layer (mRNFL), ganglion cell layer + inner plexiform layer (GCL+IPL), ganglion cell complex (GCC), and the inner limiting membrane to the retinal pigment epithelium (ILM-RPE) thickness. Retinal and choroidal thickness was compared among amblyopic, fellow, and normal eyes.
resultsIn both amblyopia groups, there was no significant difference in the mRNFL, GCL+IPL, and GCC thicknesses among the amblyopic, fellow, and control eyes. In the anisometropic amblyopia group, choroidal thickness (subfovea, center 1 mm, nasal and inferior of the inner ring, nasal of the outer ring, and center 6 mm) of amblyopic eyes were significantly greater than that of fellow and normal eyes. In contrast, none of the choroidal thicknesses were significantly different among the investigated eyes in the strabismic amblyopia group.
conclusionsWe found no significant difference in inner retinal thickness in patients with unilateral amblyopia. Although there were significant differences in choroidal thickness with hyperopic anisometropic amblyopia, there was no significant difference for the strabismic amblyopia. The discrepancy in choroidal thickness between the two types of amblyopia may be due to both differences in ocular size and underlying mechanism.
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