Evidence map›Paper›PMID 28915800›Full record

ArticleBMC psychiatry2017

Association of body mass index with amnestic and non-amnestic mild cognitive impairment risk in elderly.

Feng Wang, Minghui Zhao, Zhaoli Han, Dai Li, Shishuang Zhang, Yongqiang Zhang, Xiaodong Kong, Ning Sun, Qiang Zhang, Ping Lei

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Physical fitness and incident mild cognitive impairment: a systematic review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
    Review
  4. Article
  5. Article
  6. The role of pyroptosis in cognitive impairment.Frontiers in neuroscience · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Feng WangDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Minghui ZhaoDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Zhaoli HanDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Dai LiDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Shishuang ZhangDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Yongqiang ZhangDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Xiaodong KongDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Ning SunDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Qiang ZhangDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Ping LeiDepartment of Geriatrics, Tianjin Medical University General Hospital; Tianjin Geriatrics Institute, No. 154, Anshan Road, Heping District, Tianjin, 300052, China. leiping1974@163.com.
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies focused on the relationship between body mass index and cognitive disorder and obtained many conflicting results. This study explored the potential effects of body mass index on the risk of mild cognitive impairment (amnestic and non-amnestic) in the elderly.

methodsThe study enrolled 240 amnestic mild cognitive impairment patients, 240 non-amnestic mild cognitive impairment patients and 480 normal cognitive function controls. Data on admission and retrospective data at baseline (6 years ago) were collected from their medical records. Cognitive function was evaluated using Mini-Mental State Examination and Montreal Cognitive Assessment.

resultsBeing underweight, overweight or obese at baseline was associated with an increased risk of amnestic mild cognitive impairment (OR: 2.30, 95%CI: 1.50 ~ 3.52; OR: 1.74, 95%CI: 1.36 ~ 2.20; OR: 1.71, 95%CI: 1.32 ~ 2.22, respectively). Being overweight or obese at baseline was also associated with an increased risk of non-amnestic mild cognitive impairment (OR: 1.51, 95%CI: 1.20 ~ 1.92; OR: 1.52, 95%CI: 1.21 ~ 1.97, respectively). In subjects with normal weights at baseline, an increased or decreased body mass index at follow-up was associated with an elevated risk of amnestic mild cognitive impairment (OR: 1.80, 95%CI: 1.10 ~ 3.05; OR: 3.96, 95%CI: 2.88 ~ 5.49, respectively), but only an increased body mass index was associated with an elevated risk of non-amnestic mild cognitive impairment (OR: 1.71, 95%CI: 1.16 ~ 2.59).

conclusionsUnhealthy body mass index levels at baseline and follow-up might impact the risk of both types of mild cognitive impairment (amnestic and non-amnestic).

Indexed as

Body Mass IndexWeight GainWeight LossAgedCognitionCognitive DysfunctionFemaleHumansMaleNeuropsychological TestsObesityRetrospective StudiesRisk FactorsBody mass indexDementiaMild cognitive impairmentObesityWeight

Identifiers

PMID28915800
PMCPMC5603057
OpenAlexW2753954045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.