Association of apelin and apelin receptor with the risk of coronary artery disease: a meta-analysis of observational studies.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

1. The effect of single nucleotide polymorphisms on depression in combination with coronary diseases: a systematic review and meta-analysis.Frontiers in endocrinology · 2024
   Pooled it
2. The APLNR gene polymorphism rs7119375 is associated with an increased risk of development of essential hypertension in the Chinese population: A meta-analysis.Medicine · 2020
   Pooled it
3. Association Between Apelin Gene -1860T>C (rs56204867) Polymorphism and Coronary Artery Disease in a Syrian Cohort.Vascular health and risk management · 2026
   Article
4. The Bidirectional Relationship Between Myocardial Infarction and Depression: Risk Factors, Mechanisms, and Interventions.Biomedicines · 2025
   Review
5. Quercetin Attenuates Atherosclerosis via Modulating Apelin Signaling Pathway Based on Plasma Metabolomics.Chinese journal of integrative medicine · 2023
   Article
6. Competing Endogenous RNA Regulatory Networks of hsa_circ_0126672 in Pathophysiology of Coronary Heart Disease.Genes · 2023
   Article
7. A Review of the Roles of Apelin and ELABELA Peptide Ligands in Cardiovascular Disease, Including Heart Failure and Hypertension.Medical science monitor : international medical journal of experimental and clinical research · 2022
   Review
8. Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state.eLife · 2020
   Article
9. Association of Apelin and Apelin Receptor Polymorphisms With the Risk of Comorbid Depression and Anxiety in Coronary Heart Disease Patients.Frontiers in genetics · 2020
   Article
10. International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand.Pharmacological reviews · 2019
    Review
11. The impact of apelin and relaxin plasma levels in masked hypertension and white coat hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Article
12. Association of polymorphisms in MALAT1 with risk of coronary atherosclerotic heart disease in a Chinese population.Lipids in health and disease · 2018
    Article
13. The Role of Apelin in Cardiovascular Diseases, Obesity and Cancer.Frontiers in physiology · 2018
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as