Evidence map›Paper›PMID 28915622›Full record

ArticleOncotarget2017

Genomic analysis-integrated whole-exome sequencing of neuroblastomas identifies genetic mutations in axon guidance pathway.

Yuanyuan Li, Miki Ohira, Yong Zhou, Teng Xiong, Wen Luo, Chao Yang, Xiangchun Li, Zhibo Gao, Rui Zhou, Yohko Nakamura and 10 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Silencing of theFrontiers in pharmacology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Gene utility recapitulates chromosomal aberrancies in advanced stage neuroblastoma.Computational and structural biotechnology journal · 2022
    Article
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  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Yuanyuan Li *Life Science Research Institute, Saga Medical Center Koseikan, Saga, Japan.
Miki Ohira *Division of Cancer Genomics, Chiba Cancer Center Research Institute, Chiba, Japan.
Yong Zhou *BGI-Shenzhen, Shenzhen, China.
Teng Xiong *BGI-Shenzhen, Shenzhen, China.
Wen LuoBGI-Shenzhen, Shenzhen, China.
Chao YangBGI-Shenzhen, Shenzhen, China.
Xiangchun LiBGI-Shenzhen, Shenzhen, China.
Zhibo GaoBGI-Shenzhen, Shenzhen, China.
Rui ZhouBGI-Shenzhen, Shenzhen, China.
Yohko NakamuraDivision of Biochemistry and Innovative Cancer Therapy, Chiba Cancer Center Research Institute, Chiba, Japan.
Takehiko KamijoResearch Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan.
Yasuhiko KanekoResearch Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan.
Takeshi TaketaniDepartment of Pediatrics, Shimane University School of Medicine, Shimane, Japan.
Junichi UeyamaDivision of Pediatrics and Perinatology, Tottori University School of Medicine, Tottori, Japan.
Tatsuro TajiriDepartment of Pediatric Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hongyan ZhangBGI-Shenzhen, Shenzhen, China.
Jian WangBGI-Shenzhen, Shenzhen, China.
Huanming YangBGI-Shenzhen, Shenzhen, China.
Ye YinBGI-Shenzhen, Shenzhen, China.
Akira NakagawaraLife Science Research Institute, Saga Medical Center Koseikan, Saga, Japan.
BGI Group (China) · CNChiba Cancer Center · JPSaitama Cancer Center · JPKyoto Prefectural University of Medicine · JPShimane University · JPTottori University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma (NB) is a childhood solid malignant tumor originating from precursor cells of the peripheral nervous system. We have previously established a risk classification system based on DNA copy number profiles. To further explore the pathogenesis of NBs in distinct risk groups, we performed whole-exome sequencing analysis of 57 primary and 7 recurrent/metastatic tumors with unique chromosomal aberration profiles as categorized by our genomic sub-grouping system. Overall, a low frequency of somatic mutations was found. Besides

Indexed as

array CGHfamilial neuroblastomagenomic diversityneuroblastomawhole-exome sequencing

Identifiers

PMID28915622
PMCPMC5593593
OpenAlexW2617731187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.