ArticleJournal of critical care2018
The comparative effectiveness of noninvasive and invasive ventilation in patients with pneumonia.
Article in Journal of critical care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Oxygen use in chronic heart failure to relieve breathlessness: A systematic review.Heart failure reviews · 2020Pooled it
- Use of noninvasive versus invasive ventilation in patients hospitalized with acute exacerbation of heart failure: a Nationwide Readmissions Database study.Annals of medicine and surgery (2012) · 2026Article
- Impact of initial ventilation strategies on in-hospital mortality in sepsis patients: insights from the MIMIC-IV database.BMC pulmonary medicine · 2025Article
- Nurses' care coordination competence in mechanically ventilated patients in intensive care units: a cross-sectional study.BMC health services research · 2025Article
- Time to death and its predictors among adult patients on mechanical ventilation admitted to intensive care units in West Amhara comprehensive specialized hospitals, Ethiopia: a retrospective follow-up study.BMC anesthesiology · 2024Article
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- Article
- Survival and Healthcare Costs with Invasive Mechanical Ventilation versus Noninvasive Ventilation in Patients with Dementia Admitted with Pneumonia and Respiratory Failure.Annals of the American Thoracic Society · 2022Article
- Sequential treatment of severe pneumonia with respiratory failure and its influence on respiratory mechanical parameters and hemodynamics.World journal of clinical cases · 2022Article
- Mechanical Ventilation and Survival in Patients With Advanced Dementia in Medicare Advantage.Journal of pain and symptom management · 2022Article
- Factors and Outcomes Associated with Failed Noninvasive Positive Pressure Ventilation in Patients with Acute Respiratory Failure.International journal of general medicine · 2022Article
- Dying with dementia in Medicare Advantage, Accountable Care Organizations, or traditional Medicare.Journal of the American Geriatrics Society · 2021Article
- A scoring system derived from electronic health records to identify patients at high risk for noninvasive ventilation failure.BMC pulmonary medicine · 2021Article
- Noninvasive ventilation in critically ill very old patients with pneumonia: A multicenter retrospective cohort study.PloS one · 2021Article
- Trends in Noninvasive and Invasive Mechanical Ventilation Among Medicare Beneficiaries at the End of Life.JAMA internal medicine · 2021Article
- Factors for Predicting Noninvasive Ventilation Failure in Elderly Patients with Respiratory Failure.Journal of clinical medicine · 2020Article
- Rule-Based Cohort Definitions for Acute Respiratory Failure: Electronic Phenotyping Algorithm.JMIR medical informatics · 2020Article
- Pneumonia in exacerbations of COPD: what is the clinical significance?ERJ open research · 2020Article
- Non-invasive ventilation in the ED: Whom, When, How?Turkish journal of emergency medicine · 2018Review
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
purposeTo compare the outcomes of patients hospitalized with pneumonia treated with noninvasive ventilation (NIV) and invasive mechanical ventilation (IMV). MATERIALS AND
methodsUsing the HealthFacts multihospital electronic medical record database, we included patients hospitalized with a diagnosis of pneumonia and treated with NIV or IMV. We developed a propensity model for receipt of initial NIV and assessed the outcomes in a propensity-matched cohort, and in a covariate adjusted and propensity score weighted models.
resultsAmong 3971 ventilated patients, 1109 (27.9%) were initially treated with NIV. Patients treated with NIV were older, had lower acuity of illness score, and were more likely to have congestive heart failure and chronic pulmonary disease. Mortality was 15.8%, 29.8% and 25.9.0% among patients treated with initial NIV, initial IMV and among those with NIV failure. In the propensity matched analysis, the risk of death was lower in patients treated with NIV (relative risk: 0.71, 95% CI: 0.59-0.85). Subgroup analysis showed that NIV was beneficial among patients with cardiopulmonary comorbidities (relative risk 0.59, 95% CI: 0.47-0.75) but not in those without (relative risk 0.96, 95% CI: 0.74-0.1.25)NIV failure was significantly (p=0.002) more common in patients without cardiopulmonary conditions (21.3%) compared to those with these conditions (13.8%).
conclusionsInitial NIV was associated with better survival among the subgroup of patients hospitalized with pneumonia who had COPD or heart failure. Patients who failed NIV had high in-hospital mortality, emphasizing the importance of careful patient selection monitoring when managing severe pneumonia with NIV.
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