Evidence map›Paper›PMID 28915257›Full record

Trial reportPloS one2017

Outbreaks of epidemic keratoconjunctivitis caused by human adenovirus type 8 in the Tibet Autonomous Region of China in 2016.

Zhenqiang Lei, Zhen Zhu, Bai Ma Ci Wang, Hong Mei, Hong Li, Dan Zeng Gong Ga, Guo Jie, Mi Ma Bu Chi, Sheng Zhang, Chaofeng Ma and 1 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Current status of human adenovirus infection in China.World journal of pediatrics : WJP · 2022
    Review
  7. Review
  8. Epidemic keratoconjunctivitis: efficacy of outbreak management.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhenqiang LeiSchool of Public Health, Shaanxi University of Chinese Medicine, Xianyang city, Shaanxi province, People's Republic of China.
Zhen ZhuWHO WPRO Regional Reference Measles/Rubella laboratory and Key Laboratory of Medical Virology Ministry of Health, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing City, People's Republic of China.
Bai Ma Ci WangDepartment of Infectious Diseases, Tibet Center for Disease Control and Prevention, Lhasa city, Tibet Autonomous Region, People's Republic of China.
Hong MeiDepartment of Health Inspection, Tibet Center for Disease Control and Prevention, Lhasa city, Tibet Autonomous Region, People's Republic of China.
Hong LiDepartment of Pathogenic Biology, Medical School, Anhui University of Science and Technology, Huainan City, Anhui Province, People's Republic of China.
Dan Zeng Gong GaDepartment of Infectious Diseases, Tibet Center for Disease Control and Prevention, Lhasa city, Tibet Autonomous Region, People's Republic of China.
Guo JieGongbujiangda County Center for Disease Control and Prevention, Linzhi City, Tibet Autonomous Region, People's Republic of China.
Mi Ma Bu ChiDepartment of Infectious Diseases, Rikaze Prefecture Center for Disease Control and Prevention, Rikaze City, Tibet Autonomous Region, People's Republic of China.
Sheng ZhangWHO WPRO Regional Reference Measles/Rubella laboratory and Key Laboratory of Medical Virology Ministry of Health, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing City, People's Republic of China.
Chaofeng MaSchool of Public Health, Shaanxi University of Chinese Medicine, Xianyang city, Shaanxi province, People's Republic of China.
Wenbo XuWHO WPRO Regional Reference Measles/Rubella laboratory and Key Laboratory of Medical Virology Ministry of Health, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing City, People's Republic of China.ORCID http://orcid.org/0000-0002-5558-3018

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From April to November 2016, two outbreaks of epidemic keratoconjunctivitis (EKC) occurred successively at primary and middle schools in the Tibet Autonomous Region of China, and a total of 197 clinically diagnosed cases were reported. Real-time PCR analyses confirmed that human adenovirus (HAdV) infection was related to these outbreaks. Further studies involving sequence determination and phylogenetic analysis based on the penton base, hexon, and fiber genes indicated that human adenovirus type 8 (HAdV-8), belonging to species D, was responsible for the outbreaks. This is the first report of a HAdV-8 associated EKC outbreak in mainland of China, and the results of this study are expected to provide support for future research into HAdV-8 in China.

Indexed as

Adenoviruses, HumanConjunctivitis, ViralDisease OutbreaksAdenovirus Infections, HumanCell LineFemaleHumansMaleTibet

Identifiers

PMID28915257
PMCPMC5600394

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.