Evidence map›Paper›PMID 28915003›Full record

ArticleAccounts of chemical research2017

The Evolution of DNA-Templated Synthesis as a Tool for Materials Discovery.

Rachel K O'Reilly, Andrew J Turberfield, Thomas R Wilks

Abstract read
In one paragraph

Article in Accounts of chemical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Fuel-Driven Catalytic Molecular Templating.Journal of the American Chemical Society · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Sequencing of d/l-DNA and XNA by Templated-Synthesis.Journal of the American Chemical Society · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Rapid Chemical Ligation of DNA andJournal of the American Chemical Society · 2023
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rachel K O'ReillyDepartment of Chemistry, University of Warwick , Coventry CV4 7AL, United Kingdom.ORCID 0000-0002-1043-7172
Andrew J TurberfieldClarendon Laboratory, Department of Physics, University of Oxford , Parks Road, Oxford OX1 3PU, United Kingdom.
Thomas R WilksDepartment of Chemistry, University of Warwick , Coventry CV4 7AL, United Kingdom.ORCID 0000-0002-3067-7384

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise control over reactivity and molecular structure is a fundamental goal of the chemical sciences. Billions of years of evolution by natural selection have resulted in chemical systems capable of information storage, self-replication, catalysis, capture and production of light, and even cognition. In all these cases, control over molecular structure is required to achieve a particular function: without structural control, function may be impaired, unpredictable, or impossible. The search for molecules with a desired function is often achieved by synthesizing a combinatorial library, which contains many or all possible combinations of a set of chemical building blocks (BBs), and then screening this library to identify "successful" structures. The largest libraries made by conventional synthesis are currently of the order of 10

Indexed as

Combinatorial Chemistry TechniquesDNANucleic Acid HybridizationSmall Molecule LibrariesDNASmall Molecule Libraries

Identifiers

PMID28915003
PMCPMC5746846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.