Evidence map›Paper›PMID 28914420›Full record

ArticleJournal of natural medicines2018

Labdane-type diterpenoids from Vitex limonifolia and their antivirus activities.

Ninh Khac Ban, Nguyen Thi Kim Thoa, Tran My Linh, Do Thi Trang, Phan Van Kiem, Nguyen Xuan Nhiem, Bui Huu Tai, Chau Van Minh, Jae-Hyoung Song, Hyun-Jeong Ko and 1 more

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Article in Journal of natural medicines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Plants (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ninh Khac BanInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Nguyen Thi Kim ThoaFaculty of Basic Sciences, Hanoi University of Mining and Geology, 18 Pho Vien, Bactuliem, Hanoi, Vietnam.
Tran My LinhInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Do Thi TrangInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Phan Van KiemInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Nguyen Xuan NhiemInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Bui Huu TaiInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Chau Van MinhInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
Jae-Hyoung SongCollege of Pharmacy, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Hyun-Jeong KoCollege of Pharmacy, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Seung Hyun KimCollege of Pharmacy, Yonsei Institute of Pharmaceutical Science, Yonsei University, Songdo-dong, Yeonsu-gu, Incheon, 21983, Republic of Korea. kimsh11@yonsei.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phytochemical investigation of the methanol extract of Vitex limonifolia leaves led to the isolation of three new labdane-type diterpenoids, vitexlimolides A-C (1-3) and eight known compounds, 5,4'-dihydroxy-3,7-dimethoxyflavone (4), vitecetin (5), 5,4'-dihydroxy-7,3'-dimethoxyflavone (6), verrucosin (7), 2α, 3α-dihydroxy-urs-12-en-28-oic acid (8), euscaphlic acid (9), 18,19-seco, 2α, 3α-dihydroxy-19-oxo-urs-11,13(18)-dien-28-oic acid (10), and maslinic acid (11). Their chemical structures were elucidated by physical and chemical methods. All compounds were evaluated for antiviral activities against CVB3, HRV1B, and EV71 viruses. As a result, compounds 4 and 6 showed potent antiviral activity against CVB3 infection with IC

Indexed as

AnimalsAntiviral AgentsChlorocebus aethiopsDiterpenesDrug Screening Assays, AntitumorEnterovirus A, HumanEnterovirus B, HumanHeLa CellsHumansInhibitory Concentration 50Microbial Sensitivity TestsMolecular StructureOleanolic AcidPlant ExtractsPlant LeavesRhinovirusAntiviral AgentsDiterpeneslabdanemaslinic acidOleanolic AcidPlant ExtractsTriterpenesCoxsackievirus B3Enterovirus 71Human rhinovirusLabdaneVitex limonifolia

Identifiers

PMID28914420

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.