SynthesisEuropean child & adolescent psychiatry2018
Clinical high risk for psychosis in children and adolescents: a systematic review.
Synthesis in European child & adolescent psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictors of transition in patients with clinical high risk for psychosis: an umbrella review.Translational psychiatry · 2023Pooled it
- Clinical predictors of at-risk mental states in general adolescent population: a 2-year follow-up study.European child & adolescent psychiatry · 2026Article
- Adolescent Insomnia Disorder - Problematic Internet Use Nexus: A Convergent Developmental Trajectory - Bridging Neuroimaging Biomarkers, Molecular Susceptibility, and Environmental-Neurocognitive Cascades.Psychology research and behavior management · 2026Review
- Investigating the attenuated psychosis syndrome in youth with autism spectrum disorder: results from an observational study.Frontiers in psychiatry · 2025Article
- Multi-domain destructuring in the early phases of psychosis: a multicentric phenomenological and psychometric case-control study.Frontiers in behavioral neuroscience · 2025Article
- Clinical and neurodevelopmental predictors of psychotic disorders in children and adolescents at clinical high risk for psychosis: the CAPRIS study.European child & adolescent psychiatry · 2024Article
- The influence of complex psychiatric comorbidities on treatment for clinical high-risk for psychosis: A preliminary study.Early intervention in psychiatry · 2024Article
- Motor precision deficits in clinical high risk for psychosis.European archives of psychiatry and clinical neuroscience · 2024Article
- Age-related change in cortical thickness in adolescents at clinical high risk for psychosis: a longitudinal study.European child & adolescent psychiatry · 2024Article
- Clinical High Risk for Psychosis (CHR-P) in children and adolescents: a roadmap to strengthen clinical utility through conceptual clarity.European child & adolescent psychiatry · 2024Article
- Heterogeneity of clinical symptomatology in pediatric patients at clinical high risk for psychosis.BMC research notes · 2024Article
- Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients: what differences are there between early vs. adult onset and between schizophrenia vs. bipolar disorder?European child & adolescent psychiatry · 2024Article
- Cognitive predictors of transition and remission of psychosis risk syndrome in a child and adolescent sample: longitudinal findings from the CAPRIS study.European child & adolescent psychiatry · 2024Article
- Value of P300 amplitude in the diagnosis of untreated first-episode schizophrenia and psychosis risk syndrome in children and adolescents.BMC psychiatry · 2023Article
- Review of factors resulting in systemic biases in the screening, assessment, and treatment of individuals at clinical high-risk for psychosis in the United States.Frontiers in psychiatry · 2023Review
- Major depressive disorder and attenuated negative symptoms in a child and adolescent sample with psychosis risk syndrome: the CAPRIS study.European child & adolescent psychiatry · 2022Article
- Clinical high risk for psychosis paradigm for CAP: do not throw the baby out with the bathwater.European child & adolescent psychiatry · 2022Article
- Equity in Mental Health Services for Youth at Clinical High Risk for Psychosis: Considering Marginalized Identities and Stressors.Evidence-based practice in child and adolescent mental health · 2022Article
- Perceived Family Functioning Profile in Adolescents at Clinical High Risk for Psychosis: Rigidity as a Possible Preventive Target.Frontiers in psychiatry · 2022Article
- Prognostic Accuracy of DSM-5 Attenuated Psychosis Syndrome in Adolescents: Prospective Real-World 5-Year Cohort Study.Schizophrenia bulletin · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
The concept of being at risk for psychosis has been introduced both for adults and children and adolescents, but fewer studies have been conducted in the latter population. The aim of this study is to systematically review the articles associated with clinical description, interventions, outcome and other areas in children and adolescents at risk for psychosis. We searched in MEDLINE/PubMed and PsycINFO databases for articles published up to 30/06/16. Reviewed articles were prospective studies; written in English; original articles with Clinical High Risk (CHR) for psychosis samples; and mean age of samples younger than 18 years. From 103 studies initially selected, 48 met inclusion criteria and were systematically reviewed. Studies show that CHR children and adolescents present several clinical characteristics at baseline, with most attenuated positive-symptom inclusion criteria observed, reporting mostly perceptual abnormalities and suspiciousness, and presenting comorbid conditions such as depressive and anxiety disorders. CHR children and adolescents show lower general intelligence and no structural brain changes compared with controls. Original articles reviewed show rates of conversion to psychosis between 17 and 20% at 1 year follow-up and between 7 and 21% at 2 years. While 36% of patients recovered from their CHR status at 6-year follow-up, 40% still met CHR criteria. Studies in children and adolescents with CHR were conducted with different methodologies, assessments tools and small samples. It is important to conduct studies on psychopharmacological and psychological treatment, as well as replication of the few studies found.
Indexed as
Identifiers
28914382What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.