Evidence map›Paper›PMID 28913626›Full record

SynthesisJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

Role of

Maryam Mahmood, Ayse Tuba Kendi, Saira Farid, Saira Ajmal, Geoffrey B Johnson, Larry M Baddour, Panithaya Chareonthaitawee, Paul A Friedman, M Rizwan Sohail

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.

  1. EANM/SNMMI guideline/procedure standard for [European journal of nuclear medicine and molecular imaging · 2025
    Guideline
  2. Pooled it
  3. Article
  4. Innovations in Imaging:Current cardiology reports · 2024
    Review
  5. Review
  6. Clinical case reports · 2024
    Article
  7. Review
  8. Improved [Diagnostics (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Single-photon cardiac imaging in patients with cardiac implantable electrical devices.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Review
  18. Nuclear Imaging in Infective Endocarditis.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  19. Emergence ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  20. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
4 · The record

Corrections and comments

  • Commented on by
    2019
5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maryam MahmoodDivision of Infectious Disease, Department of Medicine, Mayo Clinic College of Medicine and Science, 200 1st Street SW, Rochester, MN, 55905, USA. mahmood.maryam@mayo.edu.
Ayse Tuba KendiDivision of Nuclear Medicine, Department of Radiology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Saira FaridDivision of Infectious Disease, Department of Medicine, Mayo Clinic College of Medicine and Science, 200 1st Street SW, Rochester, MN, 55905, USA.
Saira AjmalDivision of Infectious Disease, Department of Medicine, Mayo Clinic College of Medicine and Science, 200 1st Street SW, Rochester, MN, 55905, USA.
Geoffrey B JohnsonDivision of Nuclear Medicine, Department of Radiology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Larry M BaddourDivision of Infectious Disease, Department of Medicine, Mayo Clinic College of Medicine and Science, 200 1st Street SW, Rochester, MN, 55905, USA.
Panithaya ChareonthaitaweeDepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Paul A FriedmanDepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
M Rizwan SohailDivision of Infectious Disease, Department of Medicine, Mayo Clinic College of Medicine and Science, 200 1st Street SW, Rochester, MN, 55905, USA.
Mayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe performed a meta-analysis evaluating the use of fluorine-18-fluorodeoxyglucose (

backgroundPET/CT may be helpful in the diagnosis of CIED infection, particularly in patients with the absence of localizing signs or definitive echocardiographic findings.

methodsPubMed, Embase, Cochrane library, CINAHL, Web of Knowledge, and www.clinicaltrials.gov from January 1990 to April 2017 were searched for studies evaluating the accuracy of PET/CT in the diagnosis of CIED infections.

resultsOverall, 14 studies involving 492 patients were included in the meta-analysis. The pooled sensitivity of PET/CT for diagnosis of CIED infection was 83% (95% CI 78%-86%) and the pooled specificity was 89% (95% CI 84%-94%). PET/CT demonstrated a higher sensitivity of 96% (95% CI 86%-99%) and specificity of 97% (95% CI 86%-99%) for diagnosis of pocket infections. Diagnostic accuracy for lead infections or CIED-IE was lower with pooled sensitivity of 76% (95% CI 65%-85%) and specificity of 83% (95% CI 72%-90%).

conclusionUse of PET/CT in the evaluation of CIED infection has both a high sensitivity (83%) and specificity (89%) and deserves consideration in the management of selected patients with suspected CIED infections.

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyDefibrillators, ImplantableEndocarditisHumansPacemaker, ArtificialProsthesis-Related InfectionsRadiopharmaceuticalsFluorodeoxyglucose F18RadiopharmaceuticalsCIEDimaginginfectionmeta-analysisPET

Identifiers

PMID28913626
OpenAlexW2755478926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.