Evidence map›Paper›PMID 28913615›Full record

ArticleEuropean journal of pediatrics2018

Course of acute nonspecific mesenteric lymphadenitis: single-center experience.

Cecilia Benetti, Elisa Conficconi, Flurim Hamitaga, Marina Wyttenbach, Sebastiano A G Lava, Gregorio P Milani, Mario G Bianchetti, Giacomo D Simonetti, Rossana Helbling

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Article in European journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cecilia BenettiPediatric Department of Southern Switzerland, San Giovanni Hospital, 6500, Bellinzona, Switzerland.
Elisa ConficconiPediatric Department of Southern Switzerland, San Giovanni Hospital, 6500, Bellinzona, Switzerland.
Flurim HamitagaPediatric Department of Southern Switzerland, San Giovanni Hospital, 6500, Bellinzona, Switzerland.
Marina WyttenbachDepartment of Diagnostic Imaging, Ospedale Regionale Bellinzona e Valli, Bellinzona, Switzerland.
Sebastiano A G LavaUniversity Children's Hospital Bern and University of Bern, Bern, Switzerland.
Gregorio P MilaniPediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Mario G BianchettiPediatric Department of Southern Switzerland, San Giovanni Hospital, 6500, Bellinzona, Switzerland. mario.bianchetti@usi.ch.ORCID http://orcid.org/0000-0003-4827-6973
Giacomo D SimonettiPediatric Department of Southern Switzerland, San Giovanni Hospital, 6500, Bellinzona, Switzerland.
Rossana HelblingPediatric Department of Southern Switzerland, San Giovanni Hospital, 6500, Bellinzona, Switzerland.

Funding

research grants from the Fondazione G. & D. de Marchi ONLUS NoneThis work was supported in part by the Fondazione E. Balli and the Swiss Research Network of Clinical Pediatric Hubs None
6 · The paper itself

Abstract

Available reports dealing with acute nonspecific mesenteric lymphadenitis do not address the total duration of symptoms. However, it is commonly assumed a time for recovery ≤ 4 weeks. The purpose of this report was to investigate the course of acute nonspecific mesenteric lymphadenitis in childhood. A review was made of the patients aged ≤ 16 years in whom the diagnosis of acute nonspecific mesenteric lymphadenitis was established between 2011 and 2015 at the Pediatric Emergency Unit. The records of the Pediatric Emergency Unit, those of the referring family doctors, and the results of a structured telephone interview with each family were used. Forty-four patients (25 girls and 19 boys) aged 2.5 to 16, median 8.2, years were included. A bimodal distribution in duration of symptoms was observed: symptoms persisted for ≤ 2 weeks in 22 patients and 3 to 10 weeks in 22. Clinical and laboratory characteristics were similar in children with symptoms persisting for 2 weeks or less 28 and in those with symptoms persisting for 3-10 weeks.

conclusionIn patients affected with acute nonspecific mesenteric lymphadenitis, it is advantageous to think of the time span for recovery in terms of ≥ 4 weeks. What is Known: • Mesenteric adenitis is a self-limiting inflammatory condition with well-characterized clinical presentation and imaging features. • A total duration of symptoms of ≤ 4 weeks is usually hypothesized. What is New: • Symptoms persist for 3 to 10 weeks in half of the patients. • At presentation, clinical and laboratory characteristics are similar in children with symptoms persisting for 2 weeks or less and in those with 45 symptoms persisting for 3-10 weeks.

Indexed as

AdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMesenteric LymphadenitisPrognosisRetrospective StudiesTime FactorsAbdominal painAppendicitisLymphadenopathyMesenteric lymph nodesUltrasonography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.