Evidence map›Paper›PMID 28913559›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2018

Risk factors for implant removal after spinal surgical site infection.

Naoya Tsubouchi, Shunsuke Fujibayashi, Bungo Otsuki, Masanori Izeki, Hiroaki Kimura, Masato Ota, Takeshi Sakamoto, Akira Uchikoshi, Shuichi Matsuda

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Surgical Site Infection Management following Spinal Instrumentation Surgery: Implant Removal vs. Implant Retention: an Updated Systematical Review.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. [Effect of hydrogen peroxide on anti-infection and reducing postoperative drainage in multi-segmental lumbar surgery].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2020
    Article
  11. A prediction model of surgical site infection after instrumented thoracolumbar spine surgery in adults.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019
    Article
  12. Review
  13. Titanium granules pre-treated with hydrogen peroxide inhibit growth of bacteria associated with post-operative infections in spine surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Article
  14. The impact of deep surgical site infection on surgical outcomes after posterior adult spinal deformity surgery: a matched control study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Article
  15. The use of vacuum-assisted closure in spinal wound infections with or without exposed dura.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Naoya TsubouchiDepartment of Orthopedic Surgery, National Hospital Organization Kyoto Medical Center, 1-1 Mukaihatake-cho, Fukakusa, Fushimi, Kyoto, 612-8555, Japan. ntsubouc@kyotolan.hosp.go.jp.ORCID 0000-0001-8762-0648
Shunsuke FujibayashiDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Bungo OtsukiDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Masanori IzekiDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hiroaki KimuraDepartment of Orthopedic Surgery, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.
Masato OtaDepartment of Orthopedic Surgery, Kitano Hospital, Osaka, Japan.
Takeshi SakamotoDepartment of Orthopedic Surgery, Osaka Red Cross Hospital, Osaka, Japan.
Akira UchikoshiDepartment of Orthopedic Surgery, Wakayama Red Cross Hospital, Wakayama, Japan.
Shuichi MatsudaDepartment of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kyoto University · JPHyogo Prefectural Amagasaki General Medical Center · JPJapanese Red Cross Society Wakayama Medical Center · JPKitano Hospital · JPKyoto Medical Center · JPOsaka Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFew studies have investigated the risk factors for implant removal after treatment for spinal surgical site infection (SSI). Therefore, there is no firmly established consensus for the management of implants. We aimed to investigate the incidence and risk factors for implant removal after SSI managed with instrumentation, and to examine potential strategies for avoiding implant removal.

methodsFollowing a survey of seven spine centers, we retrospectively reviewed the records of 55 patients who developed SSI and were treated with reoperation, out of 3967 patients who had spinal instrumentation between 2003 and 2012. We examined implant survival rate and applied logistic regression analysis to assess the potential risk factors for implant removal.

resultsThe overall rate of implant retention was 60% (33/55). A higher implant retention rate was observed for posterior cervical surgery than for posterior-thoracic/lumbar surgery (100 vs. 49%, P < 0.001). On univariate analysis, significant risk factors for implant removal included greater blood loss, delay of reoperation, and delay of intervention with effective antibiotics. Multivariate analysis revealed that a delay in administering effective antibiotics was an independent and significant risk factor for implant removal in posterior-thoracic/lumbar surgery (odds ratio 1.17; 95% confidence interval 1.02-1.35, P = 0.028).

conclusionsPatients with SSI who underwent posterior cervical surgery are likely to retain the implants. Immediate administration of effective antibiotics improves implant survival in SSI treatment. Our findings can be applied to identify SSI patients at higher risk for implant removal.

Indexed as

AdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsChildDevice RemovalDrug Administration ScheduleFemaleHumansIncidenceJapanMaleMiddle AgedMultivariate AnalysisProstheses and ImplantsAnti-Bacterial AgentsImplant removalPosterior cervical surgeryPosterior thoracic surgerySpinal instrumentationSurgical site infection

Identifiers

PMID28913559
OpenAlexW2755819866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.