Evidence map›Paper›PMID 28913513›Full record

ArticleJournal of current ophthalmology2017

Choroidal thickness in non-ocular Behçet's disease - A spectral-domain OCT study.

Aman Mittal, Swetha Bindu Velaga, Khalil Ghasemi Falavarjani, Muneeswar G Nittala, Srinivas R Sadda

Open access · diamondAbstract read
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Article in Journal of current ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Choroidal involvement in systemic vasculitis: a systematic review.Journal of ophthalmic inflammation and infection · 2022
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Aman MittalKeck School of Medicine of USC, Los Angeles, CA, USA.
Swetha Bindu VelagaDoheny Eye Institute, Los Angeles, CA, USA.
Khalil Ghasemi FalavarjaniDoheny Eye Institute, Los Angeles, CA, USA.
Muneeswar G NittalaDoheny Eye Institute, Los Angeles, CA, USA.
Srinivas R SaddaDoheny Eye Institute, Los Angeles, CA, USA.
Doheny Eye Institute · USKeck Hospital of USC · USRasool Akram Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate choroidal thickness in patients with non-ocular Behçet's disease (BD) using spectral domain optical coherence tomography (SD-OCT) and to compare the results to normal eyes.

methodsIn this retrospective observational comparative study, we collected OCT and clinical data from the charts of 4 patients (7 eyes) with BD who had been referred for a screening eye exam and had a normal ocular examination. Data from 9 healthy volunteers (17 eyes) were collected as age-matched controls. The choroid was manually segmented from volume OCT scans using custom Doheny Image Reading Center OCT grading software (3D-OCTOR). Main outcome measures were choroidal thickness and intensity were compared between eyes of patients with BD and those of healthy controls.

resultsEyes of patients with non-ocular BD had significantly thinner mean central subfield choroidal thickness (227.5 ± 56.93 versus 306.85 ± 17.85,

conclusionThis study demonstrates that BD may have subclinical manifestations in the choroid, resulting in thinning of the choroid relative to normal eyes, even without overt signs of ocular involvement.

Indexed as

Behçet's diseaseChoroidal intensityChoroidal reflectivityChoroidal thicknessSpectral domain optical coherence tomography

Identifiers

PMID28913513
PMCPMC5587250
OpenAlexW2656642242

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.