Evidence map›Paper›PMID 28913507›Full record

ArticleJournal of current ophthalmology2017

Keratoconus diagnosis using Corvis ST measured biomechanical parameters.

Roghiyeh Elham, Ebrahim Jafarzadehpur, Hassan Hashemi, Kazem Amanzadeh, Fereshteh Shokrollahzadeh, Abbasali Yekta, Mehdi Khabazkhoob

Abstract read
In one paragraph

Article in Journal of current ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Regional corneal biomechanics assessment as a function of age using Strain-Stress Index maps.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Review
  6. A Novel Approach to Fabricate Early Keratoconus Phantom Models.Translational vision science & technology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Systemic and Ocular Associations of Keratoconus.Expert review of ophthalmology · 2024
    Article
  15. Article
  16. Screening of sensitiveFrontiers in bioengineering and biotechnology · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. The Shape of Corneal Deformation Alters Air Puff-Induced Loading.Frontiers in bioengineering and biotechnology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roghiyeh ElhamDepartment of Optometry, Faculty of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.
Ebrahim JafarzadehpurNoor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Hassan HashemiNoor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
Kazem AmanzadehNoor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
Fereshteh ShokrollahzadehNoor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Abbasali YektaDepartment of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Mehdi KhabazkhoobDepartment of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the diagnostic power of the Corneal Visualization Scheimpflug Technology (Corvis ST) provided corneal biomechanical parameters in keratoconic corneas.

methodsThe following biomechanical parameters of 48 keratoconic eyes were compared with the corresponding ones in 50 normal eyes: time of the first applanation and time from start to the second applanation [applanation-1 time (A1T) and applanation-2 time (A2T)], time of the highest corneal displacement [highest concavity time (HCT)], magnitude of the displacement [highest concavity deformation amplitude (HCDA)], the length of the flattened segment in the applanations [first applanation length (A1L) and second applanation length (A2L)], velocity of corneal movement during applanations [applanation-1 velocity (A1V) and applanation-2 velocity (A2V)], distance between bending points of the cornea at the highest concavity [highest concavity peak distance (HCPD)], central concave curvature at the highest concavity [highest concavity radius (HCR)]. To assess the change of parameters by disease severity, the keratoconus group was divided into two subgroups, and their biomechanical parameters were compared with each other and with normal group. The parameters' predictive ability was assessed by receiver operating characteristic (ROC) curves. To control the effect of central corneal thickness (CCT) difference between the two groups, two subgroups with similar CCT were selected, and the analyses were repeated.

resultsOf the 10 parameters compared, the means of the 8 were significantly different between groups (

conclusionsThe A1T seems a valuable parameter in the diagnosis of keratoconic eyes. It showed excellent diagnostic ability even when controlled for CCT. None of the parameters were reliable index for keratoconus staging.

Indexed as

BiomechanicsCorneaCorvis STKeratoconus

Identifiers

PMID28913507
PMCPMC5587249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.