ArticleRomanian journal of anaesthesia and intensive care2015
Changes of cortical connectivity during deep anaesthesia.
Article in Romanian journal of anaesthesia and intensive care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Into the deep end: a look at the functional changes of neuronal pathways in the deeply anesthetized state.Romanian journal of anaesthesia and intensive care · 2015Article
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7 authors.
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Abstract
BACKGROUND AND
aimsThe aim of this study was to evaluate the frontal intracortical connectivity during deep anaesthesia (burst-suppression).
methodsExperiments were carried out on 5 adult Sprague Dawley rats. The anaesthesia was induced and maintained with isoflurane. Following the induction of anaesthesia, rats were placed in a stereotactic instrument. A hole was drilled in the skull over the frontal cortex and electrodes were inserted in order to record the local field potentials. Rats were maintained in deep level anaesthesia (burst-suppression). The cortical connectivity was assessed by computing the coherence spectra. The frontal intracortical connectivity was calculated during burst, suppression (non-burst) and slow wave anaesthesia periods.
resultsThe global cortical connectivity (0.5-100 Hz) was 0.61 ± 0.078 during the burst periods compared to 0.55 ± 0.032 (p < 0.05) during the suppression periods and 0.55 ± 0.015 (p < 0.05) during slow wave anaesthesia.
conclusionsThe global cortical connectivity increased during the burst periods compared to the suppression periods and slow wave anaesthesia. This increase in the cortical synchronization might be due to the subcortical origin of the bursts.
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28913462PMC5505379What OpenQuestion holds
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