ArticleRomanian journal of anaesthesia and intensive care2014
Oxidative stress and antioxidant therapy in traumatic spinal cord injuries.
Article in Romanian journal of anaesthesia and intensive care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- α-Lipoic Acid, an Organosulfur Biomolecule a Novel Therapeutic Agent for Neurodegenerative Disorders: An Mechanistic Perspective.Neurochemical research · 2022Pooled it
- Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury.Journal of medicine and lifePooled it
- Effect of continuous intra-incisional bupivacaine on postoperative pain in non-traumatic spinal fixation surgeries: a randomized controlled trial.Brazilian journal of anesthesiology (Elsevier)Trial
- HAntioxidants (Basel, Switzerland) · 2026Article
- Serendipitous Symptom Control: Allopurinol for Spasticity in a Case of SPG4-Linked Hereditary Spastic Paraplegia-A Case Report.Clinical case reports · 2026Article
- 50 years of methylprednisolone application in spinal cord injury: a bibliometric analysis.Acta neurochirurgica · 2025Review
- Exploring the neuroprotective potential of naringin following spinal cord injury in rats: improving sensory and motor function through combating inflammation and oxidative stress.Frontiers in pharmacology · 2025Article
- Effects of albiflorin on oxidative stress and inflammatory responses in rats with acute spinal cord injury.Immunity, inflammation and disease · 2023Article
- A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities.Military Medical Research · 2023Review
- Prognostic Value of Malondialdehyde (MDA) in the Temporal Progression of Chronic Spinal Cord Injury.Journal of personalized medicine · 2023Article
- Association of Oxidative Stress with Neurological Disorders.Current neuropharmacology · 2022Article
- Polyphenols Targeting Oxidative Stress in Spinal Cord Injury: Current Status and Future Vision.Oxidative medicine and cellular longevity · 2022Review
- Identification of potential oxidative stress biomarkers for spinal cord injury in erythrocytes using mass spectrometry.Neural regeneration research · 2021Article
- Acute spinal cord injury is associated with mitochondrial dysfunction in mouse urothelium.Neurourology and urodynamics · 2019Article
- The Importance of Natural Antioxidants in the Treatment of Spinal Cord Injury in Animal Models: An Overview.Oxidative medicine and cellular longevity · 2019Review
- Yellow Laser Stimulation at GV2 Acupoint Mitigates Apoptosis, Oxidative Stress, Inflammation, and Motor Deficit in Spinal Cord Injury Rats.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Palm vitamin E reduces locomotor dysfunction and morphological changes induced by spinal cord injury and protects against oxidative damage.Scientific reports · 2017Article
- The influence of metabolic imbalances and oxidative stress on the outcome of critically ill polytrauma patients: a review.Burns & trauma · 2017Review
- Blood metabolic response to a long-term wheelchair rugby training.Spinal cord · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spinal cord injury (SCI) is often accompanied by motor, vegetative and sensitive dysfunctions that can significantly decrease the chance of the complete recovery of the patients. The pathophysiological implication of these dysfunctions is represented by the increased production of the reactive species that are extremely aggressive to the surrounding tissue. The combination of massive production of free radicals, low concentration of antioxidants and the hypermetabolism present in patients with SCI leads to enhancement of the oxidative stress. Current studies are focused on several biological active compounds that are able to reduce the effects of free radicals - tissue necrosis, inflammation, infection, apoptosis. In this paper, the mechanism of the action of several biological active compounds that are able to significantly reduce oxidative stress in critical patients with spinal cord injury is presented.
Indexed as
Identifiers
28913444PMC5505350W2181932782What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.