Evidence map›Paper›PMID 28913330›Full record

ArticleFrontiers in public health2017

Resurgence of Diphtheria in North Kerala, India, 2016: Laboratory Supported Case-Based Surveillance Outcomes.

Lucky Sangal, Sudhir Joshi, Shalini Anandan, Veeraraghavan Balaji, Jaichand Johnson, Asish Satapathy, Pradeep Haldar, Ramesh Rayru, Srinath Ramamurthy, Asha Raghavan and 1 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Respiratory Illness Caused by Corynebacterium diphtheriae and C. ulcerans, and Use of Diphtheria Antitoxin in the United States, 1996-2018.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Diphtheria resurgence in India: A case study from south Karnataka.Journal of family medicine and primary care · 2020
    Article
  14. Field-testing of primary health-care indicators, India.Bulletin of the World Health Organization · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Immune status against diphtheria in healthy adults.Journal of family medicine and primary care · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lucky SangalWHO India, World Health Organization, New Delhi, India.
Sudhir JoshiWHO India, World Health Organization, New Delhi, India.
Shalini AnandanDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Veeraraghavan BalajiDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Jaichand JohnsonState Public Health Laboratory, Thiruvananthapuram, India.
Asish SatapathyWHO India, World Health Organization, Bangalore, India.
Pradeep HaldarMinistry of Health and Family Welfare, Government of India, New Delhi, India.
Ramesh RayruMinistry of Health, Government of Kerala, Thiruvananthapuram, India.
Srinath RamamurthyWHO India, World Health Organization, Kozhikode, India.
Asha RaghavanWHO India, World Health Organization, Thiruvananthapuram, India.
Pankaj BhatnagarWHO India, World Health Organization, New Delhi, India.

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionAs part of national program, laboratory supported vaccine preventable diseases surveillance was initiated in Kerala in 2015. Mechanisms have been strengthened for case investigation, reporting, and data management. Specimens collected and sent to state and reference laboratories for confirmation and molecular surveillance. The major objective of this study is to understand the epidemiological information generated through surveillance system and its utilization for action.

methodsSurveillance data captured from reporting register, case investigation forms, and laboratory reports was analyzed. Cases were allotted unique ID and no personal identifying information was used for analysis. Throat swabs were collected from investigated cases as part of surveillance system. All

resultsA total of 533 cases were identified in 11 districts of Kerala in 2016, of which 92% occurred in 3 districts of north Kerala; Malappuram, Kozhikode, and Kannur. Almost 79% cases occurred in >10 years age group. In <18 years age group, 62% were male while in ≥18 years, 69% were females. In <10 years age group, 31% children had received three doses of diphtheria vaccine, whereas in ≥10 years, 3% cases had received all doses. Fifteen toxigenic

conclusionDiphtheria being an emerging pathogen, establishing quality surveillance for providing real-time information on disease occurrence and mortality is imperative. The epidemiological data thus generated was used for targeted interventions and to formulate vaccine policies. The data on molecular surveillance have given an insight on strain variation and transmission patterns.

Indexed as

Corynebacterium diphtheriaemolecular surveillancemulti-locus sequence typingoutbreakvaccine preventable diseases

Identifiers

PMID28913330
PMCPMC5582196

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.