ArticlePhotoacoustics2017
Feasibility of photoacoustic/ultrasound imaging of synovitis in finger joints using a point-of-care system.
Article in Photoacoustics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 85 citations in OpenAlex.
- Feasibility of the photoacoustic detection of haemophilia-related microbleeds: a preclinical study using isolated pig limbs.Thrombosis journal · 2026Article
- Development of a Dual Photoacoustic-Ultrasound Imaging System: Current Status and Future Perspectives.Sensors (Basel, Switzerland) · 2026Review
- Polymer-based ultrawideband transducers for high resolution hemispherical optoacoustic tomography.Light, science & applications · 2026Article
- Near-infrared-II pulsed laser diode array for spectral photoacoustic imaging of deep tissue oxygenation.Biomedical optics express · 2025Article
- Pulsed laser diode excitation for transcranial photoacoustics.Biomedical optics express · 2025Article
- A fast all-optical 3D photoacoustic scanner for clinical vascular imaging.Nature biomedical engineering · 2025Article
- Diode-based photoacoustic imaging for monitoring therapeutic response in rheumatoid arthritis.Biomedical optics express · 2025Article
- Multimodal PA/US imaging in Rheumatoid Arthritis: Enhanced correlation with clinical scores.Photoacoustics · 2024Article
- Quantitative evaluation of lower limb varicose veins using photoacoustic imaging.Journal of medical ultrasonics (2001) · 2024Article
- Design of a Self-Measuring Device Based on Bioelectrical Impedance Analysis for Regular Monitoring of Rheumatoid Arthritis.Sensors (Basel, Switzerland) · 2024Article
- Metabolic and molecular imaging in inflammatory arthritis.RMD open · 2024Review
- Dual-modal Photoacoustic and Ultrasound Imaging: from preclinical to clinical applications.Frontiers in photonics · 2024Article
- Mini review of photoacoustic clinical imaging: a noninvasive tool for disease diagnosis and treatment evaluation.Journal of biomedical optics · 2024Review
- Review of Three-Dimensional Handheld Photoacoustic and Ultrasound Imaging Systems and Their Applications.Sensors (Basel, Switzerland) · 2023Review
- Cylindrical lens configuration for optimizing light delivery in a curvilinear endocavity photoacoustic imaging system.Optics letters · 2023Article
- Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis.Molecules (Basel, Switzerland) · 2022Review
- Video-rate full-ring ultrasound and photoacoustic computed tomography with real-time sound speed optimization.Biomedical optics express · 2022Article
- Clinical photoacoustic/ultrasound dual-modal imaging: Current status and future trends.Frontiers in physiology · 2022Review
- In vivo optical molecular imaging of inflammation and immunity.Journal of molecular medicine (Berlin, Germany) · 2021Review
- Photoacoustic tomography reconstruction using lag-based delay multiply and sum with a coherence factor improves in vivo ovarian cancer diagnosis.Biomedical optics express · 2021Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We evaluate a portable ultrasound and photoacoustic imaging (PAI) system for the feasibility of a point-of-care assessment of clinically evident synovitis. Inflamed and non-inflamed proximal interphalangeal joints of 10 patients were examined and compared with joints from 7 healthy volunteers. PAI scans, ultrasound power Doppler (US-PD), and clinical examination were performed. We quantified the amount of photoacoustic (PA) signal using a region of interest (ROI) drawn over the hypertrophic joint space. PAI response was increased 4 to 10 fold when comparing inflamed with contralateral non-inflamed joints and with joints from healthy volunteers (p < 0.001 for both). US-PD and PAI were strongly correlated (Spearman's ρ = 0.64, with 95% CI: 0.42, 0.79). Hence, PAI using a compact handheld probe is capable of detecting clinically evident synovitis. This motivates further investigation into the predictive value of PAI, including multispectral PAI, with other established modalities such as US-PD or MRI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.