Evidence map›Paper›PMID 28913019›Full record

ArticleTurkish journal of obstetrics and gynecology2014

What should be the protocol selection after failure of in-vitro fertilization at normoresponder patients: Agonist or antagonist?

Seyit Temel Ceyhan, Yeşim Bayoğlu Tekin, Mehmet Sakinci, Cihangir Mutlu Ercan, Uğur Keskin

Open access · bronzeAbstract read
In one paragraph

Article in Turkish journal of obstetrics and gynecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Seyit Temel CeyhanGülhane Military Medical Academy, In-Vitro Fertilization Unite, Ankara, Turkey.
Yeşim Bayoğlu TekinRecep Tayyip Erdoğan University Faculty of Medicine, Department of Gynecology and Obstetrics, Rize, Turkey.
Mehmet SakinciAkdeniz University Faculty of Medicine, Department of Gynecology and Obstetrics, Antalya, Turkey.
Cihangir Mutlu ErcanGülhane Military Medical Academy, In-Vitro Fertilization Unite, Ankara, Turkey.
Uğur KeskinGülhane Military Medical Academy, In-Vitro Fertilization Unite, Ankara, Turkey.
Turkish Armed Forces · TRAkdeniz University · TRRecep Tayyip Erdoğan University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvaluation of the impact of agonist or antagonist protocol selection on pregnancy outcomes after failure of in-vitro fertilization (IVF) treatment cycles which were down regulated with Gonadotropin Releasing Hormone (GnRH) agonist. MATERIALS AND

methodsThis was a retrospective study. Two hundred and sixty nine patients who were treated with GnRH agonist protocol between years 2002-2012 at an IVF unit and underwent a second attempt following one year period after failure of IVF enrolled in the study. Age, basal FSH levels, antral follicle counts, duration of induction, the number of yielded oocytes, the number of transferred embryos and the transfer days, clinical and ongoing pregnancy rates were evaluated for each treatment cycle.

resultsNormoresponder patients were separated into two groups according to the agonist or antagonist protocol selection at the second attempt and the results of two consequent IVF cycles were compared. There were no statistically significant difference between the groups for the dosage of administered gonadotropin, duration of induction, the count of yielded oocytes, the day and the number of transferred embryos (p>0.05). Furthermore the fertilization rate, clinical and ongoing pregnancy rates were similar in two groups.

conclusionThe selection of antagonist treatment is effective as agonist protocols at normoresponder patients after failure of IVF.

Indexed as

GnRH agonistGnRH antagonistin vitro fertilizationovulation induction

Identifiers

PMID28913019
PMCPMC5558360
OpenAlexW2322715399

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.