ArticleDiabetology & metabolic syndrome2017
The relationship between insulin sensitivity and heart rate-corrected QT interval in patients with type 2 diabetes.
Article in Diabetology & metabolic syndrome, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Exploring the link between atherosclerosis indicators and QT interval in type 2 diabetes: a retrospective cross-sectional analysis.Therapeutic advances in endocrinology and metabolism · 2026Article
- Factors influencing QT interval prolongation during rifampicin-resistant tuberculosis treatment: a multicenter real-world study from China.BMC infectious diseases · 2025Article
- Prevalence of Medication Associated with QTc Prolongation Used Among Critically Ill Patients.Vascular health and risk management · 2024Article
- Obesity and Cardiac Conduction Block Disease in China.JAMA network open · 2023Article
- The influence of different glucose tolerance on QTc interval: a population-based study.BMC cardiovascular disorders · 2023Article
- Risk Factors for QT Prolongation in Patients with Chronic Hydroxychloroquine Use.Acta Cardiologica Sinica · 2022Article
- Intracellular Redistribution of Left Ventricular Connexin 43 Contributes to the Remodeling of Electrical Properties of the Heart in Insulin-resistant Elderly Rats.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2022Article
- Effects of high glucose and insulin on the electrophysiological properties of cardiomyocytes derived from human-induced pluripotent stem cells.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022Article
- Heart rate-corrected QT interval: A novel diagnostic biomarker for diabetic peripheral neuropathy.Journal of diabetes investigation · 2022Article
- Article
- Declining Levels and Bioavailability of IGF-I in Cardiovascular Aging Associate With QT Prolongation-Results From the 1946 British Birth Cohort.Frontiers in cardiovascular medicine · 2022Article
- High prevalence of prolonged QTc interval among individuals in ambulatory diabetic care in southwestern Uganda.International journal of diabetes in developing countries · 2021Article
- The relationship between adenosine deaminase and heart rate-corrected QT interval in type 2 diabetic patients.Endocrine connections · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReduced insulin sensitivity not only contributes to the pathogenesis of type 2 diabetes but is also linked to multiple metabolic risk factors and cardiovascular diseases (CVD). A prolonged heart rate-corrected QT interval (QTc interval) is related to ventricular arrhythmias and CVD mortality and exhibits a high prevalence among type 2 diabetes patients. The aim of the study was to investigate the relationship between insulin sensitivity and the QTc interval in patients with type 2 diabetes.
methodsThis cross-sectional observational study recruited 2927 patients with type 2 diabetes who visited the Affiliated Haian Hospital and Second Affiliated Hospital of Nantong University. The insulin sensitivity index (Matsuda index, ISI
resultsThe QTc interval was significantly and negatively correlated with the ISI
conclusionsReduced insulin sensitivity is associated with an increase in the QTc interval in patients with type 2 diabetes.
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