Evidence map›Paper›PMID 28912760›Full record

ArticleFrontiers in microbiology2017

Immunization with Live Human Rhinovirus (HRV) 16 Induces Protection in Cotton Rats against HRV14 Infection.

Mira C Patel, Lioubov M Pletneva, Marina S Boukhvalova, Stefanie N Vogel, Adriana E Kajon, Jorge C G Blanco

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. A COVID-19 human viral challenge model. Learning from experience.Influenza and other respiratory viruses · 2020
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mira C PatelSigmovir Biosystems, Inc., RockvilleMD, United States.
Lioubov M PletnevaSigmovir Biosystems, Inc., RockvilleMD, United States.
Marina S BoukhvalovaSigmovir Biosystems, Inc., RockvilleMD, United States.
Stefanie N VogelUniversity of Maryland School of Medicine, BaltimoreMD, United States.
Adriana E KajonInfectious Disease Program, Lovelace Respiratory Research Institute, AlbuquerqueNM, United States.
Jorge C G BlancoSigmovir Biosystems, Inc., RockvilleMD, United States.
Sigmovir Biosystems (United States) · USLovelace Respiratory Research Institute · USUniversity of Maryland, Baltimore · US

Funding

Development of the Cotton Rat Model of Rhinovirus Infection and DiseaseR21AI101480 · NIAID · SIGMOVIR BIOSYSTEMS, INC. · PI BLANCO, JORGE C · 2012 to 2013
$513k
NIAID NIH HHS R21 AI101480
6 · The paper itself

Abstract

Human rhinoviruses (HRVs) are the main cause of cold-like illnesses, and currently no vaccine or antiviral therapies against HRVs are available to prevent or mitigate HRV infection. There are more than 150 antigenically heterogeneous HRV serotypes, with ∼90 HRVs belonging to major group species A and B. Development of small animal models that are susceptible to infection with major group HRVs would be beneficial for vaccine research. Previously, we showed that the cotton rat (

Indexed as

asthmacotton ratcross-protectionrhinovirusesvaccines

Identifiers

PMID28912760
PMCPMC5583225
OpenAlexW2752761965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.