Evidence map›Paper›PMID 28912672›Full record

ArticleFrontiers in neuroscience2017

Maximizing the Potential of Longitudinal Cohorts for Research in Neurodegenerative Diseases: A Community Perspective.

Catherine J Moody, Derick Mitchell, Grace Kiser, Dag Aarsland, Daniela Berg, Carol Brayne, Alberto Costa, Mohammad A Ikram, Gail Mountain, Jonathan D Rohrer and 3 more

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Towards capturing meaningful outcomes for people with dementia in psychosocial intervention research: A pan-European consultation.Health expectations : an international journal of public participation in health care and health policy · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Catherine J MoodyMedical Research Council Head OfficeLondon, United Kingdom.
Derick MitchellIrish Platform for Patient Organisations, Science and IndustryDublin, Ireland.
Grace KiserEU Joint Programme - Neurodegenerative Disease ResearchParis, France.
Dag AarslandCentre for Age-Related Medicine, Stavanger University HospitalStavanger, Norway.
Daniela BergDepartment of Neurology, Christian-Albrechts-University of KielKiel, Germany.
Carol BrayneCambridge Institute of Public Health, University of CambridgeCambridge, United Kingdom.
Alberto CostaIRCCS Fondazione Santa LuciaRome, Italy.
Mohammad A IkramErasmus University Medical CentreRotterdam, Netherlands.
Gail MountainSchool of Health and Related Research, University of SheffieldSheffield, United Kingdom.
Jonathan D RohrerDementia Research Centre, University College London Institute of NeurologyLondon, United Kingdom.
Charlotte E TeunissenVU University Medical CentreAmsterdam, Netherlands.
Leonard H van den BergDepartment of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center UtrechtUtrecht, Netherlands.
Joanna M WardlawCentre for Clinical Brain Sciences, UK Dementia Research Institute at the University of EdinburghEdinburgh, United Kingdom.

Funding

Medical Research Council MR/J009482/1Medical Research Council MR/K026992/1Medical Research Council MR/M008525/1Medical Research Council MR/M023664/1
6 · The paper itself

Abstract

Despite a wealth of activity across the globe in the area of longitudinal population cohorts, surprisingly little information is available on the natural biomedical history of a number of age-related neurodegenerative diseases (ND), and the scope for intervention studies based on these cohorts is only just beginning to be explored. The Joint Programming Initiative on Neurodegenerative Disease Research (JPND) recently developed a novel funding mechanism to rapidly mobilize scientists to address these issues from a broad, international community perspective. Ten expert Working Groups, bringing together a diverse range of community members and covering a wide ND landscape [Alzheimer's, Parkinson's, frontotemporal degeneration, amyotrophic lateral sclerosis (ALS), Lewy-body and vascular dementia] were formed to discuss and propose potential approaches to better exploiting and coordinating cohort studies. The purpose of this work is to highlight the novel funding process along with a broad overview of the guidelines and recommendations generated by the ten groups, which include investigations into multiple methodologies such as cognition/functional assessment, biomarkers and biobanking, imaging, health and social outcomes, and pre-symptomatic ND. All of these were published in reports that are now publicly available online.

Indexed as

flexible funding mechanismjoint programminglongitudinal cohort studiesneurodegenerative diseaseresearchtransnational working groups

Identifiers

PMID28912672
PMCPMC5582201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.