ArticleScientific reports2017
The Cacna1h mutation in the GAERS model of absence epilepsy enhances T-type Ca
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 43 citations in OpenAlex.
- A novelExperimental biology and medicine (Maywood, N.J.) · 2026Article
- Calcium Ions in the Physiology and Pathology of the Central Nervous System.International journal of molecular sciences · 2024Review
- The T-type calcium channelosome.Pflugers Archiv : European journal of physiology · 2024Review
- Secretory carrier-associated membrane protein 5 regulates cell-surface targeting of T-type calcium channels.Channels (Austin, Tex.) · 2023Article
- The role of molecular chaperones in the mechanisms of epileptogenesis.Cell stress & chaperones · 2023Review
- MEPIRAPIM-derived synthetic cannabinoids inhibit T-type calcium channels with divergent effects on seizures in rodent models of epilepsy.Frontiers in physiology · 2023Article
- Genomic and Non-Genomic Regulatory Mechanisms of the Cardiac Sodium Channel in Cardiac Arrhythmias.International journal of molecular sciences · 2022Review
- Secretory carrier-associated membrane protein 2 (SCAMP2) regulates cell surface expression of T-type calcium channels.Molecular brain · 2022Article
- Splice-variant specific effects of a CACNA1H mutation associated with writer's cramp.Molecular brain · 2021Article
- A Versatile Clustered Regularly Interspaced Palindromic Repeats Toolbox to Study Neurological CaFrontiers in molecular neuroscience · 2021Article
- Voltage-Gated CaFrontiers in synaptic neuroscience · 2021Review
- Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene.Molecular neurobiology · 2020Article
- A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of CaMolecular brain · 2020Article
- Ghrelin Selectively Inhibits CaMolecular neurobiology · 2020Article
- Genetic T-type calcium channelopathies.Journal of medical genetics · 2020Review
- Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.Brain : a journal of neurology · 2020Article
- Compound heterozygous CACNA1H mutations associated with severe congenital amyotrophy.Channels (Austin, Tex.) · 2019Article
- CACHD1 is an α2δ-Like Protein That Modulates CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Selective inhibition of CaScience signaling · 2018Article
- T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.Molecular brain · 2018Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Low-voltage-activated T-type calcium channels are essential contributors to the functioning of thalamocortical neurons by supporting burst-firing mode of action potentials. Enhanced T-type calcium conductance has been reported in the Genetic Absence Epilepsy Rat from Strasbourg (GAERS) and proposed to be causally related to the overall development of absence seizure activity. Here, we show that calnexin, an endoplasmic reticulum integral membrane protein, interacts with the III-IV linker region of the Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.