Evidence map›Paper›PMID 28912528›Full record

ArticleScientific reports2017

Extracellular vesicles derived from T regulatory cells suppress T cell proliferation and prolong allograft survival.

Sistiana Aiello, Federica Rocchetta, Lorena Longaretti, Silvia Faravelli, Marta Todeschini, Linda Cassis, Francesca Pezzuto, Susanna Tomasoni, Nadia Azzollini, Marilena Mister and 6 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 111 citations in OpenAlex.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Sistiana AielloIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Federica RocchettaIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Lorena LongarettiIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Silvia FaravelliIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Marta TodeschiniIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Linda CassisInstitut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain.
Francesca PezzutoIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Susanna TomasoniIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Nadia AzzolliniIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Marilena MisterIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Caterina MeleIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Sara ContiIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Matteo BrenoIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Giuseppe RemuzziIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Marina NorisIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy. marina.noris@marionegri.it.ORCID 0000-0001-7651-5033
Ariela BenigniIRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Centro Ricerche Trapianti Chiara Cucchi de Alessandri e Gilberto Crespi Ranica, Bergamo, Italy.
Mario Negri Institute for Pharmacological Research · ITHospital del Mar Research Institute · ESUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have previously shown that rat allogeneic DC, made immature by adenoviral gene transfer of the dominant negative form of IKK2, gave rise in-vitro to a unique population of CD4

Indexed as

Immune ToleranceAllograftsAnimalsExtracellular VesiclesImmunosuppressive AgentsRatsT-Lymphocytes, RegulatoryImmunosuppressive Agents

Identifiers

PMID28912528
PMCPMC5599553
OpenAlexW2754195618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.