Evidence map›Paper›PMID 28912279›Full record

ArticleAJNR. American journal of neuroradiology2017

Differences in Morphologic and Hemodynamic Characteristics for "PHASES-Based" Intracranial Aneurysm Locations.

N Varble, H Rajabzadeh-Oghaz, J Wang, A Siddiqui, H Meng, A Mowla

Open access · bronzeAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Application of convolutional network models in detection of intracranial aneurysms: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 6 countries.

N VarbleFrom the Department of Mechanical and Aerospace Engineering (N.V., H.R.-O., H.M.).ORCID http://orcid.org/0000-0003-2273-7962
H Rajabzadeh-OghazFrom the Department of Mechanical and Aerospace Engineering (N.V., H.R.-O., H.M.).ORCID http://orcid.org/0000-0002-9138-9239
J WangDepartments of Biostatistics (J.W., A.M.).ORCID http://orcid.org/0000-0002-2709-5332
A SiddiquiToshiba Stroke and Vascular Research Center (N.V., H.R.-O., A.S., H.M.).ORCID http://orcid.org/0000-0002-9519-0059
H MengFrom the Department of Mechanical and Aerospace Engineering (N.V., H.R.-O., H.M.).ORCID http://orcid.org/0000-0003-3884-499X
A MowlaDepartments of Biostatistics (J.W., A.M.) mowla_a@yahoo.com.ORCID http://orcid.org/0000-0001-5352-8747
Toshiba (Japan) · JPMRC Biostatistics Unit · GBYahoo (Spain) · ES

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Virtual Intervention of Intracranial AneurysmsR01NS091075 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MENG, HUI · 2015 to 2019
$1.7M
AView: A Bedside Simulation Tool for Neurovascular InterventionR03NS090193 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MENG, HUI · 2015 to 2016
$157k
NCATS NIH HHS UL1 TR001412NINDS NIH HHS R01 NS091075NINDS NIH HHS R03 NS090193
6 · The paper itself

Abstract

background and purposeSeveral recent prospective studies have found that unruptured intracranial aneurysms at various anatomic locations have different propensities for future rupture. This study aims to uncover the lack of understanding regarding rupture-prone characteristics, such as morphology and hemodynamic factors, associated with different intracranial aneurysm location. MATERIALS AND

methodsWe investigated the characteristics of 311 unruptured aneurysms at our center. Based on the PHASES study, we separated and compared morphologic and hemodynamic characteristics among 3 aneurysm location groups: 1) internal carotid artery; 2) middle cerebral artery; and 3) anterior communicating, posterior communicating, and posterior circulation arteries.

resultsA mixed model statistical analysis showed that size ratio, low wall shear stress area, and pressure loss coefficient were different between the intracranial aneurysm location groups. In addition, a pair-wise comparison showed that ICA aneurysms had lower size ratios, lower wall shear stress areas, and lower pressure loss coefficients compared with MCA aneurysms and compared with the group of anterior communicating, posterior communicating, and posterior circulation aneurysms. There were no statistical differences between MCA aneurysms and the group of anterior communicating, posterior communicating, and posterior circulation aneurysms for morphologic or hemodynamic characteristics.

conclusionsICA aneurysms may be subjected to less rupture-prone morphologic and hemodynamic characteristics compared with other locations, which could explain the decreased rupture propensity of intracranial aneurysms at this location.

Indexed as

AgedAneurysm, RupturedCarotid Artery, InternalFemaleHemodynamicsHumansIntracranial AneurysmMaleMiddle AgedMiddle Cerebral ArteryProspective StudiesStress, Mechanical

Identifiers

PMID28912279
PMCPMC5819012
OpenAlexW2755206425

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.