Trial reportArchives of disease in childhood2018
Neonatal resuscitation using a laryngeal mask airway: a randomised trial in Uganda.
Trial report in Archives of disease in childhood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Clinical Trial Assessing Laryngeal Mask Airway (LMA) Versus Face-mask Ventilation (FMV) in Neonatal Resuscitation at Mulago Hospital, Uganda
Neonatal Supraglottic Airway Trial: A Single-centre, Open-label, Randomized Clinical Trial to Evaluate the Efficacy of I-gel® Supraglottic Airway Used in Neonatal Resuscitation in Reducing Early Neonatal Mortality and Morbidity
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 9. Neonatal resuscitation.Clinical and experimental emergency medicine · 2026Guideline
- Comparison of laryngeal mask airway and endotracheal tube placement in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2024Trial
- Effect of sustained inflation on pharmacokinetics and pharmacodynamics of endotracheal and supraglottic airway epinephrine in a neonatal piglet model.Pediatric research · 2026Article
- Preterm Supraglottic Airways Succeed in Neonatal Resuscitation Simulations.Acta paediatrica (Oslo, Norway : 1992) · 2026Observational
- Pharmacokinetics and pharmacodynamics of endotracheal versus supraglottic airway epinephrine in a healthy neonatal piglet model.Pediatric research · 2025Article
- Updates in neonatal resuscitation: routine use of laryngeal masks as an alternative to face masks.Clinical and experimental pediatrics · 2024Article
- Exploring the role of laryngeal masks in neonatal resuscitation.Clinical and experimental pediatrics · 2024Article
- Dependence of Successful Airway Management in Neonatal Simulation Manikins on the Type of Supraglottic Airway Device and Providers' Backgrounds.Children (Basel, Switzerland) · 2024Article
- Significance of Neonatal Heart Rate in the Delivery Room-A Review.Children (Basel, Switzerland) · 2023Review
- Laryngeal mask airway in neonatal stabilization and transport: a retrospective study.European journal of pediatrics · 2023Article
- Review
- Time to Effective Ventilation in Neonatal Manikins with a Supraglottic Airway vs. a Facemask: A Randomized Controlled Trial.Children (Basel, Switzerland) · 2023Article
- Use of laryngeal mask for neonatal resuscitation in Brazil: A national survey.Resuscitation plus · 2023Article
- Article
- One-rescuer newborn CPR using a face mask or an i-gel supraglottic airway and two-finger compressions - A manikin study with cross-over desgin.Resuscitation plus · 2022Article
- Implementation of Surfactant Administration through Laryngeal or Supraglottic Airways (SALSA): A Jordanian NICU's Journey to Improve Surfactant Administration.Children (Basel, Switzerland) · 2022Article
- Proficiency of Laryngeal Mask Airway Insertion Skill in NRP Certified Providers.American journal of perinatology · 2022Article
- Reply to: "The strength of a randomized controlled trial lies in its design-randomization".Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Laryngeal Masks in Neonatal Resuscitation-A Narrative Review of Updates 2022.Children (Basel, Switzerland) · 2022Review
- Review of investigational medical devices' clinical trials and regulations in Africa as a benchmark for new innovations.Frontiers in medical technology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMortality rates from birth asphyxia in low-income countries remain high. Face mask ventilation (FMV) performed by midwives is the usual method of resuscitating neonates in such settings but may not always be effective. The i-gel is a cuffless laryngeal mask airway (LMA) that could enhance neonatal resuscitation performance. We aimed to compare LMA and face mask (FM) during neonatal resuscitation in a low-resource setting.
settingMulago National Referral Hospital, Kampala, Uganda.
designThis prospective randomised clinical trial was conducted at the labour ward operating theatre. After a brief training on LMA and FM use, infants with a birth weight >2000 g and requiring positive pressure ventilation at birth were randomised to resuscitation by LMA or FM. Resuscitations were video recorded.
main outcome measuresTime to spontaneous breathing.
resultsForty-nine (24 in the LMA and 25 in the FM arm) out of 50 enrolled patients were analysed. Baseline characteristics were comparable between the two arms. Time to spontaneous breathing was shorter in LMA arm than in FM arm (mean 153 s (SD±59) vs 216 s (SD±92)). All resuscitations were effective in LMA arm, whereas 11 patients receiving FM were converted to LMA because response to FMV was unsatisfactory. There were no adverse effects.
conclusionA cuffless LMA was more effective than FM in reducing time to spontaneous breathing. LMA seems to be safe and effective in clinical practice after a short training programme. Its potential benefits on long-term outcomes need to be assessed in a larger trial. CLINICAL TRIAL REGISTRY: This trial was registered in https://clinicaltrials.gov, with registration number NCT02042118.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.