Evidence map›Paper›PMID 28912125›Full record

ArticleThe Journal of cell biology2017

BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites.

Dharm S Patel, Sarah M Misenko, Joonyoung Her, Samuel F Bunting

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 93 citations in OpenAlex.

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  20. The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dharm S PatelDepartment of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ.ORCID 0000-0003-1804-838X
Sarah M MisenkoDepartment of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ.ORCID 0000-0003-2088-5670
Joonyoung HerDepartment of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ.
Samuel F BuntingDepartment of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ bunting@cabm.rutgers.edu.ORCID 0000-0002-4629-496X
Rutgers, The State University of New Jersey · US

Funding

UMDNJ TRAINING GRANT IN BIOTECHNOLOGYT32GM008339 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI YARMUSH, MARTIN L · 1989 to 2019
$6.1M
Control of Commitment Steps in Mammalian Homologous RecombinationR01CA190858 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI BUNTING, SAMUEL · 2015 to 2021
$2.1M
NCI NIH HHS R01 CA190858NIGMS NIH HHS T32 GM008339
6 · The paper itself

Abstract

The

Indexed as

DNA Breaks, Double-StrandedRecombinational DNA RepairAnimalsBRCA1 ProteinBRCA2 ProteinCell Line, TumorCell SurvivalDNA-Binding ProteinsGenomic InstabilityGenotypeHumansLymphocytesMice, KnockoutMutationNeoplasmsPhenotypeBloom syndrome proteinBRCA1 ProteinBRCA1 protein, humanBrca1 protein, mouseBRCA2 ProteinBRCA2 protein, humanDNA-Binding ProteinsRAD51 protein, humanRad51 protein, mouseRad51 RecombinaseRecQ HelicasesTrp53bp1 protein, mouseTumor Suppressor p53-Binding Protein 1Tumor Suppressor ProteinsXRCC2 protein, human

Identifiers

PMID28912125
PMCPMC5674892
OpenAlexW2754242788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.